200345-63-7

Basic information

• Product Name: (Z)-2-Azido-3-(2-trifluoromethyl-phenyl)-acrylic acid ethyl ester
• Synonyms: (Z)-2-Azido-3-(2-trifluoromethyl-phenyl)-acrylic acid ethyl ester
• CAS NO: 200345-63-7
• Molecular Weight: 285.226
• Mol File: 200345-63-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-2-Azido-3-(2-trifluoromethyl-phenyl)-acrylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-2-Azido-3-(2-trifluoromethyl-phenyl)-acrylic acid ethyl ester(200345-63-7)
• EPA Substance Registry System: (Z)-2-Azido-3-(2-trifluoromethyl-phenyl)-acrylic acid ethyl ester(200345-63-7)

Safety Data

• Hazardous Substances Data: 200345-63-7(Hazardous Substances Data)

Upstream product

• 200345-65-9 2-Azido-3-hydroxy-3-(2-trifluoromethyl-phenyl)-propionic acid ethyl ester 
• 637-81-0 ethyl-2-azidoacetate 
• 447-61-0 2-Trifluoromethylbenzaldehyde 

Downstream Products

• 317-60-2 4-trifluoromethyl-indole-2-carboxylic acid ethyl ester 

Relevant articles and documents

New findings on the hemetsberger-knittel reaction (synthetic studies on indoles and related compounds. XLIII(1))

In the Hemetsberger-Knittel reaction for indole synthesis, the intermediate ethyl 2-azido-3-hydroxy-3-aryl-propionate (4) was found to be formed in the reaction of arylaldehyde 1 with ethyl azidoacetate at a lower temperature (-30°C) as the main product,