200568-20-3

Basic information

• Product Name: 6-α-hydroxy-2'-O-triethylsilyl-7-α-paclitaxel
• Synonyms: 6-α-hydroxy-2'-O-triethylsilyl-7-α-paclitaxel
• CAS NO: 200568-20-3
• Molecular Weight: 984.182
• Mol File: 200568-20-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6-α-hydroxy-2'-O-triethylsilyl-7-α-paclitaxel(CAS DataBase Reference)
• NIST Chemistry Reference: 6-α-hydroxy-2'-O-triethylsilyl-7-α-paclitaxel(200568-20-3)
• EPA Substance Registry System: 6-α-hydroxy-2'-O-triethylsilyl-7-α-paclitaxel(200568-20-3)

Safety Data

• Hazardous Substances Data: 200568-20-3(Hazardous Substances Data)

Upstream product

• 288153-43-5 C₆₇H₈₅NO₁₇Si₂ 
• 288153-46-8 C₆₇H₈₅NO₁₇Si₂ 

Downstream Products

• 200568-21-4 C₅₄H₆₃NO₁₅SSi 
• 200568-22-5 C₅₃H₆₅NO₁₄Si 
• 200568-48-5 C₅₃H₆₅NO₁₄Si 
• 200568-47-4 C₅₃H₆₃NO₁₄Si 
• 288153-43-5 C₆₇H₈₅NO₁₇Si₂ 
• 288153-46-8 C₆₇H₈₅NO₁₇Si₂ 
• 212953-26-9 2'-O-triethylsilylpaclitaxel-6,7-β-cyclic sulfate 
• 212953-29-2 2'-O-triethylsilylpaclitaxel-6-α-nitrate 
• 153212-75-0 [3H]-6alpha-Hydroxypaclitaxel 
• 153212-75-0 6-α-hydroxy-7-α-paclitaxel 
• 340820-41-9 C₅₃H₆₄BrNO₁₄Si 
• 212953-27-0 C₅₃H₆₄FNO₁₄Si 
• 340820-40-8 C₅₃H₆₄ClNO₁₄Si 
• 212953-25-8 6-β-hydroxy-2'-O-triethylsilylpaclitaxel 

Relevant articles and documents

Stereospecific synthesis of the major human metabolite of paclitaxel

The stereospecific synthesis of 6-α-hydroxy paclitaxel 10, the major human metabolite of paclitaxel, is described. The 6,7-α-diol 4, obtained from paclitaxel, is converted to the 6,7-β-cyclic sulfate followed by nitrate addition and reduction to afford the title compound. (C) 2000 Elsevier Science Ltd.