200635-82-1Relevant articles and documents
Preparation of 2-(3-Hydroxyalkylthio)benzoxazoles and their Conversion into Thietanes
Ikemizu, Dai,Matsuyama, Ayako,Takemura, Kazunori,Mitsunobu, Oyo
, p. 1247 - 1248 (2007/10/03)
Reaction of primary or secondary 1,3-diols with dibenzoxazol-2-yl disulfide and tributylphosphine or triphenylphosphine selectively gave 2-(3-hydroxyalkylthio)benzoxazoles which, on treatment with KH, were converted into the corresponding thietanes. 2,2-Dibenzylthietane-1-oxide reacted with silylated purines and pyrimidines in the presence of TMSOTf and ZnI2 to give the corresponding thietane nucleosides in 17-69% yields.