20080-09-5

Basic information

• Product Name: 3-(4-methylphenyl)-5-phenyl-4,5-dihydroisoxazole
• CAS NO: 20080-09-5
• Molecular Weight: 237.301
• Mol File: 20080-09-5.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: 3-(4-methylphenyl)-5-phenyl-4,5-dihydroisoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-methylphenyl)-5-phenyl-4,5-dihydroisoxazole(20080-09-5)
• EPA Substance Registry System: 3-(4-methylphenyl)-5-phenyl-4,5-dihydroisoxazole(20080-09-5)

Safety Data

• Hazardous Substances Data: 20080-09-5(Hazardous Substances Data)

Upstream product

• 148730-42-1 1-(4-methylphenyl)-2-phenylcyclopropane 
• 100-42-5 styrene 
• 36288-37-6 N-hydroxy-4-methylbenzenecarboximidoyl chloride 
• 106-42-3 para-xylene 
• 13820-14-9 4-methylbenzonitrile oxide 
• 104-87-0 4-methyl-benzaldehyde 
• 56363-35-0 1-methyl-4-(2-phenylcyclopropyl)benzene 
• 3717-15-5 p-methylbenzaldehyde oxime 
• 4224-96-8 3-phenyl-1-p-tolylprop-2-en-1-one 
• 3235-02-7 p-methylbenzaldehyde oxime 

Downstream Products

• 134430-88-9 (2E)-N-(4-methylphenyl)-3-phenylprop-2-enamide 
• 181121-98-2 (Z)-N-(4-metilfenil)-3-fenilpropenamida 
• 25855-99-6 1-(4-methylphenyl)-3-phenyl-1,3-propanedione 
• 2431-23-4 4-methylbenzoin 
• 52939-89-6 5-phenyl-4-p-tolyl-2,5-dihydro-oxazole 
• 52939-91-0 anti-p-Tolyl-cis-styryl-ketoxim 
• 52939-90-9 (Z)-3-amino-1-phenyl-3-(4-methylphenyl)-prop-2-en-1-one 
• 55955-83-4 syn/anti-p-Tolyl-trans-styryl-ketoxim 

Relevant articles and documents

Palladium-Catalyzed Synthesis ofΔ2-Isoxazoline from Toluene Derivatives Enabled by the Triple Role of Silver Nitrate

A palladium-catalyzed direct synthesis ofΔ2-isoxazoline from toluene derivatives has been established. The present reaction proceeds through nondirected Csp3-H activation, benzylic nitration, dehydration, and cycloaddition. This protocol also features the unusual triple role of silver nitrate in a one-pot reaction.

Hypervalent iodine-catalyzed cycloaddition of nitrile oxides to alkenes

A new and convenient method for preparation of isoxazolines was developed by a catalytic cycloaddition of nitrile oxides generated in situ from aldoximes to alkenes in the presence of a catalytic amount of iodobenzene. In this protocol, iodobenzene was fi

An environmentally benign synthesis of isoxazolines and isoxazoles mediated by potassium chloride in water

An effective and environmentally benign procedure for the synthesis of isoxazolines and isoxazoles has been developed by a cycloaddition of nitrile oxides with alkenes or alkynes in water. In this approach, potassium chloride is first oxidized into chlorine in water by the environmentally friendly oxidant Oxone, then aldoximes are oxidized into nitrile oxides by the in situ generated hypochlorous acid, finally a 1,3-dipolar cycloaddition between nitrile oxides and alkenes or alkynes occurs to provide the corresponding isoxazolines and isoxazoles in good yields.