200956-20-3

Basic information

• Product Name: 1-(BENZYLOXY)-4-(2,2,2-TRIFLUOROETHOXY)BENZENE
• Synonyms: 1-(BENZYLOXY)-4-(2,2,2-TRIFLUOROETHOXY)BENZENE;1-BENZYLOXY-4-TRIFLUOROETHOXYBENZENE;1-(Benzyloxy)-4-(2,2,2-trifluoroethoxy)benzene 98%;1-(Benzyloxy)-4-(2,2,2-trifluoroethoxy)benzene98%
• CAS NO: 200956-20-3
• Molecular Formula: C₁₅H₁₃F₃O₂
• Molecular Weight: 282.26
• Mol File: 200956-20-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 335.6°Cat760mmHg
• Flash Point: 164.8°C
• Appearance: /
• Density: 1.221g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.511
• CAS DataBase Reference: 1-(BENZYLOXY)-4-(2,2,2-TRIFLUOROETHOXY)BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(BENZYLOXY)-4-(2,2,2-TRIFLUOROETHOXY)BENZENE(200956-20-3)
• EPA Substance Registry System: 1-(BENZYLOXY)-4-(2,2,2-TRIFLUOROETHOXY)BENZENE(200956-20-3)

Safety Data

• Hazard Codes: Xi
• Safety Statements: 24/25
• Hazardous Substances Data: 200956-20-3(Hazardous Substances Data)

Usage

General Description

1-(benzyloxy)-4-(2,2,2-trifluoroethoxy)benzene is a chemical compound with the molecular formula C15H13F3O2. It is a clear, colorless liquid with a molecular weight of 288.26 g/mol. 1-(BENZYLOXY)-4-(2,2,2-TRIFLUOROETHOXY)BENZENE is commonly used as a building block for the synthesis of various pharmaceuticals and agrochemicals. It is also used in the production of specialty chemicals and as a reagent in organic synthesis. 1-(benzyloxy)-4-(2,2,2-trifluoroethoxy)benzene has potential applications in the field of medicine, agriculture, and chemical research due to its unique chemical properties. It is important to handle this chemical with caution as it may pose health and safety risks if not properly managed.

InChI:InChI=1/C15H13F3O2/c16-15(17,18)11-20-14-8-6-13(7-9-14)19-10-12-4-2-1-3-5-12/h1-9H,10-11H2

Upstream product

• 103-16-2 4-Benzyloxyphenol 
• 6226-25-1 2,2,2-trifluoroethyl trifluoromethanesulphonate 
• 75-89-8 2,2,2-trifluoroethanol 
• 146631-00-7 [4-(benzyloxy)phenyl]boronic acid 
• 433-06-7 2,2,2-Trifluoroethyl p-toluenesulfonate 

Downstream Products

• 129560-99-2 4-(2,2,2-trifluoroethoxy)phenol 
• 444341-80-4 2-chloro-4-(2,2,2-trifluoroethoxy)phenol 
• 444341-81-5 3-bromopropyl 2-chloro-4-(2,2,2-trifluoroethoxy)phenyl ether 
• 103-16-2 4-Benzyloxyphenol 

Relevant articles and documents

THERAPEUTIC AGENT FOR INFLAMMATORY DISEASES, AUTOIMMUNE DISEASES, FIBROTIC DISEASES, AND CANCER DISEASES

A therapeutic agent for treating at least one disease selected from the group consisting of inflammatory diseases, autoimmune diseases, fibrotic diseases, and cancer diseases, comprising: at least one selected from the group consisting of a compound represented by the following general formula (1) and pharmacologically acceptable salts thereof as an active ingredient. [In the formula (1), R1 and R2 may be the same or different and each represents a hydrogen atom, a halogen atom, a hydroxyl group, a carboxy group, a cyano group, an optionally substituted C1-6 alkyl group et al.; R3 represents a hydrogen atom; R4 represents an optionally substituted 4- to 10-membered monocyclic heterocyclic group containing 1 to 4 heteroatoms selected from an oxygen atom, a nitrogen atom, and a sulfur atom; X represents a group represented by the following formula: -CH2-, - CH2-CH2-, -CH2-CH2-CH2-, or -CH2-O-CH2-; and Z represents a hydrogen atom or a hydroxyl group.]

Facile synthesis of trifluoroethyl aryl ethers through copper-catalyzed coupling of CF3CH2OH with aryl- and heteroaryl boronic acids

An efficient copper-catalyzed Chan-Lam reaction of trifluoroethanol with a variety of aryl- and heteroaryl boronic acids has been developed. This research provides a practical method to synthesize trifluoroethyl aryl ethers in moderate to good yields under mild conditions.

(2R)-2-Methylchromane-2-carboxylic acids: Discovery of selective PPARα agonists as hypolipidemic agents

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