201036-12-6Relevant articles and documents
Substance, with protein tyrosine kinase inhibitory activity, and preparation method and application thereof
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Paragraph 0173-0175, (2020/04/08)
The invention discloses substances having a protein tyrosine kinase inhibitory activity, and a preparation method and a use thereof; the substances are compounds having the structure represented by the general formula V, wherein in the formula V, X is sul
Synthesis and radioprotective effects of novel benzyl naphthyl sulfoxide (sulfone) derivatives transformed from Ex-RAD
Tang, Lin,Peng, Tao,Wang, Gang,Wen, Xiaoxue,Sun, Yunbo,Zhang, Shouguo,Liu, Shuchen,Wang, Lin
supporting information, p. 625 - 631 (2018/05/03)
In this work, a series of novel benzyl naphthyl sulfoxides (sulfones) derived from Ex-RAD were designed and synthesized as potential radioprotective agents. Some of the compounds considerably protected HUVECs against 60Co γ-irradiation, accompanied by the absence of cytotoxicity. Compared to Ex-RAD, compound 8n not only exhibited a significant protective effect on cell survival and radiation-induced DNA damage, but also remarkably enhanced the survival (100%) of mice in 30 days after being exposed to irradiation. The results suggested that some target compounds are valuable for further research as promising radioprotectors.
Chiral microporous Ti(salan)-based metal-organic frameworks for asymmetric sulfoxidation
Zhu, Chengfeng,Chen, Xu,Yang, Zhiwei,Du, Xia,Liu, Yan,Cui, Yong
, p. 7120 - 7122 (2013/08/23)
Chiral porous metal-metallosalan frameworks are constructed from an unsymmetrical chiral pyridinecarboxylate ligand derived from Ti(salan) and are shown to be heterogeneous catalysts for asymmetric oxidation of thioethers to sulfoxides.
