201211-16-7Relevant articles and documents
Adenosine deaminase inhibitors: Synthesis and biological evaluation of unsaturated, aromatic, and oxo derivatives of (+)-erythro-9-(2'S-hydroxy-3'R-nonyl)adenine [(+)-EHNA]
Pragnacharyulu,Varkhedkar,Curtis,Chang,Abushanab
, p. 4694 - 4700 (2007/10/03)
The synthesis and biological evaluation of three classes of chain-modified derivatives of (+)-EHNA are described. Among the 5',6'-unsaturated derivatives, the Z-isomer was the most potent inhibitor of adenosine deaminase (ADA) but 3-fold less active than
