201227-38-5 Usage
General Description
5-Bromo-1H-indazole-3-carbaldehyde is a chemical compound with the molecular formula C8H6BrN3O. It is a derivative of indazole, which is commonly used as a building block in the synthesis of various pharmaceutical compounds and organic molecules. 5-BROMO-1H-INDAZOLE-3-CARBALDEHYDE is a key intermediate in the preparation of biologically active molecules and has potential applications in the pharmaceutical industry. It is known for its ability to selectively react with various nucleophiles to form a wide range of chemical products. Additionally, it can be used as a starting material for the synthesis of heterocyclic compounds, which are important in drug discovery and development. Overall, 5-Bromo-1H-indazole-3-carbaldehyde is a versatile chemical with important potential uses in organic synthesis and drug research.
Check Digit Verification of cas no
The CAS Registry Mumber 201227-38-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,1,2,2 and 7 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 201227-38:
(8*2)+(7*0)+(6*1)+(5*2)+(4*2)+(3*7)+(2*3)+(1*8)=75
75 % 10 = 5
So 201227-38-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H5BrN2O/c9-5-1-2-7-6(3-5)8(4-12)11-10-7/h1-4H,(H,10,11)
201227-38-5Relevant articles and documents
An optimized procedure for direct access to 1: H -indazole-3-carboxaldehyde derivatives by nitrosation of indoles
Chevalier, Arnaud,Ouahrouch, Abdelaaziz,Arnaud, Alexandre,Gallavardin, Thibault,Franck, Xavier
, p. 13121 - 13128 (2018/04/23)
Indazole derivatives are currently drawing more and more attention in medicinal chemistry as kinase inhibitors. 1H-indazole-3-carboxaldehydes are key intermediates to access to a variety of polyfunctionalized 3-substituted indazoles. We report here a general access to this motif, based on the nitrosation of indoles in a slightly acidic environment. These very mild conditions allow the conversion of both electron-rich and electron-deficient indoles into 1H-indazole-3-carboxaldehydes.
