201294-65-7

Basic information

• Product Name: 1-benzyl-5-(hydroxymethyl)pyridin-2(1H)-one
• Synonyms: 1-benzyl-5-(hydroxymethyl)pyridin-2(1H)-one
• CAS NO: 201294-65-7
• Molecular Weight: 215.252
• Mol File: 201294-65-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-benzyl-5-(hydroxymethyl)pyridin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-5-(hydroxymethyl)pyridin-2(1H)-one(201294-65-7)
• EPA Substance Registry System: 1-benzyl-5-(hydroxymethyl)pyridin-2(1H)-one(201294-65-7)

Safety Data

• Hazardous Substances Data: 201294-65-7(Hazardous Substances Data)

Upstream product

• 58584-63-7 (6-methoxypyridin-3-yl)methanol 
• 100-39-0 benzyl bromide 
• 26218-80-4 6-methoxy-nicotinic acid methyl ester 
• 66572-55-2 6-methoxynicotinic acid 
• 4332-79-0 1-benzyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid 

Downstream Products

• 744212-68-8 (±)-1-benzyl-5-(hydroxymethyl)piperidin-2-one 
• 201294-66-8 1-benzyl-6-oxo-1,6-dihydropyridine-3-carbaldehyde 

Relevant articles and documents

Synthesis and reduction reactions of pyridones and 5-acyl-2-methoxypyridines

The synthesis of a series of pyridones, from their 2-hydroxypyridine or 2-methoxypyridine precursors, is described, along with studies into their reductions to saturated heterocycles. A number of 5-acylpyridones were prepared and were evaluated as substrates for asymmetric transfer hydrogenation prior to conversion to saturated heterocycles. The enantioselective reduction of 5-acetyl-1-benzylpyrimidine-2,4(1H,3H)-dione is also described.