201336-47-2

Basic information

• Product Name: 4-Amino-N-[4-(3-ethyl-2,6-dioxo-piperidin-3-yl)-phenyl]-benzenesulfonamide
• Synonyms: 4-Amino-N-[4-(3-ethyl-2,6-dioxo-piperidin-3-yl)-phenyl]-benzenesulfonamide
• CAS NO: 201336-47-2
• Molecular Weight: 387.459
• Mol File: 201336-47-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Amino-N-[4-(3-ethyl-2,6-dioxo-piperidin-3-yl)-phenyl]-benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Amino-N-[4-(3-ethyl-2,6-dioxo-piperidin-3-yl)-phenyl]-benzenesulfonamide(201336-47-2)
• EPA Substance Registry System: 4-Amino-N-[4-(3-ethyl-2,6-dioxo-piperidin-3-yl)-phenyl]-benzenesulfonamide(201336-47-2)

Safety Data

• Hazardous Substances Data: 201336-47-2(Hazardous Substances Data)

Upstream product

• 125-84-8 aminoglutethimide 
• 98-62-4 4-aminobenzenesulfonyl fluoride 

Relevant articles and documents

Sulfonylamido derivatives of aminoglutethimide and their copper(II) complexes: A novel class of antifungal compounds

Reaction of aminoglutethimide (3-(4-aminophenyl)-3-ethyl-2,6-piperidinedione) with sulfonyl halides or sulfonic acid anhydrides affords a series of 3-[4-(alkyl/arylsulfonylamido)phenyl]-3-ethyl-2,6-piperidinediones. Some of these derivatives, containing free amino groups, have been further derivatized by reaction with 2,4,6-trimethylpyrylium perchlorate, 3,4-dichlorophenyl isocyanate or tosyl isocyannte. Cu(II) complexes containing as ligands the conjugate bases of some of these compounds have also been obtained. The new derivatives generally act as moderate antifungal agents against Aspergillus and Candida spp, but one of them shows activities comparable to ketoconazole.