201595-65-5 Usage
Description
D-[UL-13C6]FRUCTOSE, also known as D-Fructose-13C6, is an isotopically labeled monosaccharide that naturally occurs in a large number of fruits and plants. It is used as an internal standard for the quantification of D-fructose by gas chromatography (GC) or liquid chromatography-mass spectrometry (LC-MS). D-Fructose is a ubiquitous monosaccharide derived from the breakdown of sucrose by sucrase in the intestine and serves as a precursor in the biosynthesis of D-fructose-1,6-bisphosphate, an intermediate in the production of D-glucose via gluconeogenesis. Deficiencies in the enzymes that metabolize D-fructose can lead to inborn errors of metabolism, with varying severity depending on the specific enzyme deficiency. Increased consumption of D-fructose has been associated with obesity, dyslipidemia, and impaired insulin sensitivity.
Uses
Used in Pharmaceutical Industry:
D-[UL-13C6]FRUCTOSE is used as an internal standard for the quantification of D-fructose in pharmaceutical research and development. This application is crucial for ensuring accurate measurements and reliable results in the analysis of D-fructose levels in various pharmaceutical formulations and biological samples.
Used in Metabolic Research:
In the field of metabolic research, D-[UL-13C6]FRUCTOSE is used as a research tool to study the metabolism of D-fructose and its role in various inborn errors of metabolism. This helps researchers understand the underlying mechanisms of these conditions and develop potential therapeutic strategies.
Used in Nutritional Science:
D-[UL-13C6]FRUCTOSE is used as a research tool in nutritional science to investigate the effects of D-fructose consumption on obesity, dyslipidemia, and impaired insulin sensitivity. This application aids in understanding the relationship between D-fructose intake and metabolic health, which can inform dietary recommendations and public health policies.
Used in Food Industry:
In the food industry, D-[UL-13C6]FRUCTOSE can be used as a reference material for the development and validation of analytical methods for the detection and quantification of D-fructose in various food products. This ensures the accuracy and reliability of D-fructose measurements, which is essential for product labeling and quality control purposes.
Used in Clinical Diagnostics:
D-[UL-13C6]FRUCTOSE is used as an internal standard in clinical diagnostics to measure D-fructose levels in patient samples, such as blood or urine. This application is important for the diagnosis and monitoring of inborn errors of metabolism and other conditions related to D-fructose metabolism.
Used in Environmental Science:
In environmental science, D-[UL-13C6]FRUCTOSE can be used as a tracer to study the fate and transport of D-fructose in the environment, particularly in relation to agricultural runoff and wastewater treatment processes. This information can help inform strategies for managing and mitigating the environmental impacts of D-fructose.
Check Digit Verification of cas no
The CAS Registry Mumber 201595-65-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,1,5,9 and 5 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 201595-65:
(8*2)+(7*0)+(6*1)+(5*5)+(4*9)+(3*5)+(2*6)+(1*5)=115
115 % 10 = 5
So 201595-65-5 is a valid CAS Registry Number.
InChI:InChI=1/C6H12O6/c7-2-6(11)5(10)4(9)3(8)1-12-6/h3-5,7-11H,1-2H2/t3-,4-,5+,6?/m1/s1/i1+1,3+1,4+1,5+1,6+1
201595-65-5Relevant articles and documents
Integration of Enzymatic and Heterogeneous Catalysis for One-Pot Production of Fructose from Glucose
Sun, Jiankui,Li, Helong,Huang, Hongzhi,Wang, Bo,Xiao, Ling-Ping,Song, Guoyong
, p. 1157 - 1162 (2018/03/21)
The search for efficient routes for the production of fructose from biomass-derived glucose is of great interest and importance, as fructose is a highly attractive substrate in the conversion of cellulosic biomass into biofuels and chemicals. In this study, a one-pot, multistep procedure involving enzyme-catalyzed oxidation of glucose at C2 and Ni/C-catalyzed hydrogenation of d-glucosone at C1 selectively gives fructose in 77 % yield. Starting from upstream substrates such as α-cellulose and starch, fructose was also generated with similar efficiency and selectivity by the combination of enzymatic and heterogeneous catalysis. This method constitutes a new means of preparing fructose from biomass-derived substrates in an efficient fashion.
