201684-34-6

Basic information

• Product Name: Toluene-4-sulfonic acid 5-bromo-3-formyl-1H-indol-7-yl ester
• CAS NO: 201684-34-6
• Molecular Weight: 394.246
• Mol File: 201684-34-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Toluene-4-sulfonic acid 5-bromo-3-formyl-1H-indol-7-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Toluene-4-sulfonic acid 5-bromo-3-formyl-1H-indol-7-yl ester(201684-34-6)
• EPA Substance Registry System: Toluene-4-sulfonic acid 5-bromo-3-formyl-1H-indol-7-yl ester(201684-34-6)

Safety Data

• Hazardous Substances Data: 201684-34-6(Hazardous Substances Data)

Upstream product

• 201684-59-5 5-bromo-7-(p-toluenesulfonyloxy)indole-2-carboxylic acid 
• 126260-58-0 ethyl 5-bromo-7-tosyloxyindole-2-carboxylate 
• 68-12-2 N,N-dimethyl-formamide 
• 201684-32-4 5-bromo-7-(p-toluenesulfonyloxy)indole 

Downstream Products

• 126260-53-5 2-{2-[5-Bromo-7-(toluene-4-sulfonyloxy)-1H-indol-3-yl]-ethylcarbamoyl}-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 201684-38-0 Toluene-4-sulfonic acid 6-bromo-1-(4,5-dihydro-3H-pyrrol-2-yl)-4,9-dihydro-3H-β-carbolin-8-yl ester 
• 201684-57-3 5-bromo-7-(p-toluenesulfonyloxy)tryptamine 
• 102673-53-0 6-Bromo-1-(4,5-dihydro-3H-pyrrol-2-yl)-9H-β-carbolin-8-ol 
• 126260-54-6 Toluene-4-sulfonic acid 6-bromo-1-(4,5-dihydro-3H-pyrrol-2-yl)-9H-β-carbolin-8-yl ester 
• 126260-59-1 (E)-5-bromo-3-nitrovinyl-7-(p-toluenesulfonyloxy)indole 

Relevant articles and documents

Fischer indolization of 2-sulfonyloxyphenylhydrazones: A new and practical approach for preparing 7-oxygenated indoles and application to the first synthesis of eudistomidin-A. (Fischer indolization and its related compounds. Part 28)

An efficient method for synthesis of 7-oxygenated indoles was established by Fischer indolization of the phenylhydrazones (10) with a sulfonyloxy group at the ortho-position. This method was applied to the first synthesis of the calmodulin antagonist eudistomidin-A (2).