201855-41-6

Basic information

• Product Name: H-SER(TBU)-AMC HCL
• Synonyms: H-Ser(tBu)-AMC;O-tert-Butyl-L-serine 7-amido-4-methylcoumarin hydrochloride;SERINE(TBU)-AMC HCL;O-T-BUTYL-L-SERINE 7-AMIDO-4-METHYLCOUMARIN HYDROCHLORIDE;H-SER(TBU)-AMC HCL
• CAS NO: 201855-41-6
• Molecular Formula: C17H23ClN2O4
• Molecular Weight: 354.83
• Mol File: 201855-41-6.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: -15°C
• CAS DataBase Reference: H-SER(TBU)-AMC HCL(CAS DataBase Reference)
• NIST Chemistry Reference: H-SER(TBU)-AMC HCL(201855-41-6)
• EPA Substance Registry System: H-SER(TBU)-AMC HCL(201855-41-6)

Safety Data

• Hazardous Substances Data: 201855-41-6(Hazardous Substances Data)

Usage

Description

H-SER(TBU)-AMC HCL is a specific chemical compound that consists of a serine amino acid with a tert-butyl (TBU) group attached, combined with 7-amino-4-methylcoumarin (AMC) and hydrochloric acid (HCL). It is a valuable tool in biochemical research and drug development due to its unique properties.
Used in Biochemical Research:
H-SER(TBU)-AMC HCL is used as a substrate in enzyme assays for measuring the activity of proteases, particularly serine proteases. The presence of the AMC group allows for the detection of enzymatic activity through fluorescence, providing a reliable and sensitive method for assessing protease function.
Used in Drug Development:
H-SER(TBU)-AMC HCL is used as a tool in drug development to study and screen potential inhibitors of serine proteases. By monitoring the fluorescence changes upon enzymatic activity, researchers can evaluate the effectiveness of candidate compounds in inhibiting protease activity, which is crucial for the development of new therapeutic agents targeting protease-related diseases.
Used in Laboratory Settings:
H-SER(TBU)-AMC HCL is used as a stable and soluble compound in laboratory settings. The presence of hydrochloric acid provides stability and solubility to the compound, making it easier to work with and handle in various experimental procedures. This feature is particularly important for maintaining the integrity and consistency of the compound during research and development processes.