2020-73-7

Basic information

• Product Name: 1-Butanone, 1-(2,4,5-trimethoxyphenyl)-
• CAS NO: 2020-73-7
• Molecular Formula: C13H18O4
• Molecular Weight: 238.284
• Mol File: 2020-73-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-Butanone, 1-(2,4,5-trimethoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Butanone, 1-(2,4,5-trimethoxyphenyl)-(2020-73-7)
• EPA Substance Registry System: 1-Butanone, 1-(2,4,5-trimethoxyphenyl)-(2020-73-7)

Safety Data

• Hazardous Substances Data: 2020-73-7(Hazardous Substances Data)

Usage

Appearance

Pale yellow, oily liquid

Aroma

Strong sweet, spicy

Occurrence

Commonly found in essential oils such as clove oil, nutmeg, and cinnamon

Usage

Flavoring agent in food industry, fragrance in perfumes and personal care products

Antibacterial properties

Makes it a popular ingredient in dental products such as mouthwash and toothpaste

Antioxidant properties

Adds to its usefulness in various products

Potential applications

Pharmaceuticals and natural insect repellent.

Upstream product

• 18113-18-3 2,5-dimethoxyphenol 
• 106-31-0 butanoic acid anhydride 
• 135-77-3 1,2,4-trimethoxy-benzene 
• 1421-63-2 2,4,5-Trihydroxybutyrophenone 
• 77-78-1 dimethyl sulfate 
• 2015-80-7 2,5-Dihydroxy-4-methoxy-butyrophenon 
• 141-75-3 butyryl chloride 
• 186581-53-3 diazomethane 
• 105475-57-8 1-(5-hydroxy-2,4-dimethoxy-phenyl)-butan-1-one 
• 105476-01-5 1-(4-hydroxy-2,5-dimethoxy-phenyl)-butan-1-one 
• 121-33-5 vanillin 
• 2015-55-6 Methoxy-hydrochinon-dibutyrat 
• 824-46-4 methoxyhydroquinone 

Downstream Products

• 83893-42-9 methyl 2-(2,4,5-trimethoxyphenyl)butyrate 
• 83893-50-9 methyl 2-(4-methoxy-3,6-dioxo-1,4-cyclohexadienyl)butyrate 
• 392286-93-0 5-n-butyl-1,2,4-trimethoxybenzene 
• 90834-07-4 α-bromo-2,4,5-trimethoxybutyrophenone 
• 3905-27-9 4-(2',4',5'-trimethoxyphenyl)butanoic acid 
• 76236-93-6 2,4,5-trimethoxy-α-n-propylbenzenemethanol 
• 76252-27-2 trans-4-(2′,4′,5′-trimethoxyphenyl)but-3-ene 

Relevant articles and documents

Substituted methoxybenzene derivatives: C8H9NO4, C9H11NO5 and C13H18O4

The structures of three methoxybenzenes, namely 1,2-dimethoxy-4-nitrobenzene, C8H9NO4, (I), 1,2,3-trimethoxy-5-nitrobenzene, C9H11NO5, (II), and 1-(2,4,5-trimethoxyphenyl)-1-butanone, C13H18O4, (III), are reported. Molecules of (I) and (III) are planar, but one of the three methoxy groups of (II) is twisted out of the phenyl ring plane as a result of steric hindrance. In all three solids, the molecules are linked to form centrosymmetrically hydrogen-bonded dimers; they are packed in parallel layers in (I) and (II), but in zigzag layers in (III).

Synthesis and hypolipidemic activity of modified side chain α-asarone homologues

A series of homologues of α-asarone (1), containing variable size and functionality on the side chain attached to the aromatic ring, has been subjected to a study of structure-activity relationship. For most of the prepared derivatives, either with a carbonyl (8a-8e), a hydroxy group (9a-9e), or with a conjugated double bond (10a-10d), significant effects on serum lipoprotein cholesterol, LDL-cholesterol, HDL-cholesterol and triglycerides were displayed. The results showed an enhancement of the hypocholesterolemic activity as the length of the chain is decreased. Theoretical conformational and electrostatic potential analyses of 1 and olefins 10 suggest unfavorable steric interactions in the bulky superior side-chain homologues as the deactivating biological effect.