20205-30-5Relevant articles and documents
Two different donor subunits substituted unsymmetrical squaraines for solution-processed small molecule organic solar cells
Yang, Daobin,Jiao, Yan,Huang, Yan,Zhuang, Taojun,Yang, Lin,Lu, Zhiyun,Pu, Xuemei,Sasabe, Hisahiro,Kido, Junji
, p. 179 - 186 (2016)
Two unsymmetrical squaraines (USQs) with different donor (D) subunits as photovoltaic materials, namely USQ-11 and USQ-12, were designed and synthesized to investigate the effect of different D subunits on the optoelectronic properties of USQs for the first time. The two USQs compounds were characterized for optical, electrochemical, quantum chemical and optoelectronic properties. By changing the two different D subunits attached to the squaric acid core from 2,3,3-trimethylindolenine to 2-methylbenzothiazole, the HOMO energy levels could be tuned with a stepping of 0.07 eV, and quite different solid state aggregations (H-or J-aggregation) were observed in the thin film by UV-Vis absorption spectra, which were attributed to their distinct steric effects and dipole moments. Solution-processed bulk-heterojunction small molecule organic solar cells fabricated with the USQ-11/PC71BM (1:5, wt%) exhibited extremely higher PCE (4.27%) than that of the USQ-12/PC71BM (2.78%). The much enhanced PCE should be attributed to the simultaneously improved Voc, Jsc and FF.
Synthesis of asymmetric monomethine cyanine dyes with red-shifted optical properties
Soriano, Eduardo,Outler, Loretta,Owens, Eric A.,Henary, Maged
, p. 180 - 184 (2015)
Six novel asymmetrical monomethine cyanine dyes were synthesized via the condensation reaction of 1-butyl-2-(methylthio)benzo[c,d]indol-1-ium iodide and various 1,5-substituted indolenine salts under basic conditions. The dyes were characterized using UV-vis spectroscopy, fluorescence, 1H NMR, 13C NMR, and mass spectrometry; furthermore, the purity of these compounds was observed using LC/ELSD/MS.
Fluorescence properties of indolenine semi-squarylium dyes
Matsui, Masaki,Shibata, Toshihiro,Fukushima, Masato,Kubota, Yasuhiro,Funabiki, Kazumasa
, p. 9936 - 9941,6 (2012)
3-Butoxy-4-(1-butyl-3,3-dimethyl-3H-indol-2-ylidenemethyl)-3-cyclobut-1, 2-dione exhibited the most intense florescence at fluorescence maxima 536 and 563 nm with fluorescence quantum yield 0.21 among any indolenine semi-squarylium dyes in the crystalline form due to the isolated dimer-type molecular packing and its suitable melting point. This compound showed aggregation-induced emission enhancement.
Acridinium-conjugated aromatic heterocycles as highly potent FtsZ inhibitors: Design, synthesis, and biological evaluation
Chen, Weijin,Guo, Ting,Ma, Shutao,Ma, Yangchun,Song, Di,Zhang, Nan,Zhang, Shenyan
, (2022/03/15)
The epidemic of multidrug resistance (MDR) is a serious threat to public health, and new classes of antibiotics with novel mechanisms of action are in critical need. We rationally designed and efficiently synthesized three series of new chemical entities with potential antibacterial activity targeting filamenting temperature-sensitive mutant Z (FtsZ). Evaluation of these compounds against a panel of Gram-positive bacteria including MDR and vancomycin-resistant Enterococcus?strains indicated that most compounds showed enhanced antibacterial efficacy, comparable or even superior to the reference drugs. The newly synthesized compounds proved to be substrates of the Escherichia coli efflux pump AcrB, thus affecting the activity. Their structure–activity relationships?were summarized in detail. The most potent compound 10f quickly eliminated bacteria in a bactericidal mode, with low susceptibility to induce bacterial resistance. Further mechanistic studies with the BsFtsZ protein revealed that 10f functioned as an effective FtsZ inhibitor through altering the dynamics of FtsZ self-polymerization via a stimulatory mechanism, which leads to inhibition of cell division and cell death. Besides, 10f not only displayed no obvious cytotoxicity to mammalian cells but also had a high efficacy in a murine model of bacteremia in vivo. Regarded as a whole, our findings highlight 10f as a promising new FtsZ-targeting bactericidal agent.
NOVEL SQUARYLIUM COMPOUNDS, AND COMPOSITIONS COMPRISING SAME
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Paragraph 0142; 0144-0146, (2021/04/29)
The present disclosure is disclosed herein. The present invention relates to a novel squarylium compound and a near infrared absorbing resin composition containing the squarylium compound.
Tuning lipophilicity for optimizing the H2S sensing performance of coumarin-merocyanine derivatives
Fang, Hongbao,Chen, Yuncong,Shi, Xiangchao,Bai, Yang,Chen, Zhongyan,Han, Zhong,Zhang, Yuming,He, Weijiang,Guo, Zijian
supporting information, p. 14800 - 14805 (2019/09/30)
Hydrogen sulfide (H2S) is an endogenous signaling molecule involved in various physiopathological processes; coumarin-based merocyanines have been successfully utilized for developing fluorescent H2S sensors. However, subtle changes in the chemical structure of merocyanines could induce distinct difference in the H2S sensing behavior. Investigation of the structure-property relationship of merocyanine dyes is of great importance for the development of ideal sensors with desirable performance. In this work, a series of coumarin/merocyanine (CMC) hybrid fluorescent probes with different lipophilicities have been developed. By altering the N-alkyl chain, the reaction rate with H2S and intracellular distribution of CMC sensors are optimized. The results showed that increasing the lipophilicity by attaching longer N-alkyl chains leads to a faster sensing response as well as a higher efficiency of the mitochondrial targeting ability. By virtue of rapid sensing of H2S and impressive mitochondrial co-localization ability, CM-NC6 could monitor H2S levels via a dual channel ratiometric mode. In addition, CM-NC6 is also capable of in vivo imaging of exogenous H2S. The work provided a powerful strategy for developing H2S sensors with optimized performance, which would be helpful for understanding the complicated roles of H2S in various physiological processes.
