202123-10-2

Basic information

• Product Name: (4-Chloro-benzyl)-[1-methyl-3-phenyl-prop-(E)-ylidene]-amine
• CAS NO: 202123-10-2
• Molecular Weight: 271.79
• Mol File: 202123-10-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-Chloro-benzyl)-[1-methyl-3-phenyl-prop-(E)-ylidene]-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (4-Chloro-benzyl)-[1-methyl-3-phenyl-prop-(E)-ylidene]-amine(202123-10-2)
• EPA Substance Registry System: (4-Chloro-benzyl)-[1-methyl-3-phenyl-prop-(E)-ylidene]-amine(202123-10-2)

Safety Data

• Hazardous Substances Data: 202123-10-2(Hazardous Substances Data)

Upstream product

• 2550-26-7 4-Phenyl-2-butanone 
• 104-86-9 4-chlorobenzylamine 

Downstream Products

• 4187-57-9 (S)-1-methyl-3-phenylpropylamine 
• 937-52-0 (R)-1-methyl-3-phenylpropylamine 

Relevant articles and documents

Asymmetric imine isomerisation in the enantioselective synthesis of chiral amines from prochiral ketones

An asymmetric catalytic synthesis of chiral amines using a chiral base catalysed [1,3]-proton shift reaction of imines is described. The isomerisation reaction of N-benzylimines 2a-b derived from prochiral ketones (benzylacetone, acetophenone) and p-substituted benzylamines, is catalysed by chiral alcohols and aminoalcohols 5-12 and gives enantiomerically enriched (up to 44% e.e.) N-benzylidene derivatives 3a-b. The resulting products 3a-b are readily hydrolysed to their corresponding amines 4a-b.