202271-71-4

Basic information

• Product Name: Cbz-DL-α-methylglutamic acid
• Synonyms: Cbz-DL-α-methylglutamic acid
• CAS NO: 202271-71-4
• Molecular Weight: 295.292
• Mol File: 202271-71-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Cbz-DL-α-methylglutamic acid(CAS DataBase Reference)
• NIST Chemistry Reference: Cbz-DL-α-methylglutamic acid(202271-71-4)
• EPA Substance Registry System: Cbz-DL-α-methylglutamic acid(202271-71-4)

Safety Data

• Hazardous Substances Data: 202271-71-4(Hazardous Substances Data)

Upstream product

• 71-90-9 2-methylglutamic acid 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 71-90-9 2-methylglutamic acid 

Relevant articles and documents

Microbial enantioselective removal of the N-benzyloxycarbonyl amino protecting group

In order to deprotect N-carbobenzoxy-l-aminoacids (Cbz-AA) and related compounds, a series of microorganisms was selected from soil by enrichment cultures with Cbz-l-Glu as sole nitrogen source. A lyophilized whole-cell preparation of two Arthrobacter sp. strains grown on Cbz-Glu or Cbz-Gly exhibited a high cleavage activity. The conditions of hydrolysis have been optimized and a quantitative enantioselective deprotection of several Cbz-dl-amino acids was obtained, as well as the deprotection of N-carbamoylester derivatives of several synthetic amino compounds. The preparation of Cbz-d-allylglycine and l-allylglycine in high yield and high optical purity is described as an application of this method.