20239-99-0 Usage
Description
Pheophorbide b is a chlorophyll-related pigment derived from the breakdown of chlorophyll. It is a green pigment found in plants, algae, and some bacteria, playing a role in photosynthesis and the process of chlorophyll degradation. Pheophorbide b has garnered interest for its potential applications in photodynamic therapy for cancer treatment, as well as for its antioxidant and anti-inflammatory properties, making it a promising candidate for pharmaceutical and nutraceutical industries.
Uses
Used in Photodynamic Therapy for Cancer Treatment:
Pheophorbide b is used as a photosensitizer for inducing apoptosis in cancer cells when activated by light. It has shown promising results in the treatment of various types of cancer, including solid tumors.
Used in Pharmaceutical Industry:
Pheophorbide b is used as a potential candidate for the development of pharmaceutical products due to its antioxidant and anti-inflammatory properties. These properties may contribute to the prevention and treatment of various diseases and conditions.
Used in Nutraceutical Industry:
Pheophorbide b is used as a potential ingredient in nutraceutical products for its health-promoting benefits. Its antioxidant and anti-inflammatory properties may support overall health and well-being.
However, it is important to note that further research is needed to fully understand the potential benefits and risks of using pheophorbide b in medical and industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 20239-99-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,2,3 and 9 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 20239-99:
(7*2)+(6*0)+(5*2)+(4*3)+(3*9)+(2*9)+(1*9)=90
90 % 10 = 0
So 20239-99-0 is a valid CAS Registry Number.
20239-99-0Relevant articles and documents
Synthesis of Covalently Linked dimeric Derivatives of Chlorophyll a, Pyrochlorophyll a, Chlorophyll b, and Bacteriochlorophyll a
Wasielewski, Michael R.,Svec, Walter A.
, p. 1969 - 1974 (2007/10/02)
Bis(chlorophyllide) ethylene glycol diesters were prepared for each of the title compounds.Pheophytins a and b isolated from alfalfa and bacteriochlorophyll a isolated from R.sphaeroides were treated with 80percent aqueous trifluoroacetic acid to yield the corresponding pheorbides.Pyropheophorbide was prepared by a literature procedure.Carbonic anhydride and benzotriazole-1-methanesulfonate activation methods were used in the esterification of the pheophorbides with ethylene glycol at ambient temperature.Each method yielded 75percent+ of the pheophorbide ethylene glycol monoester.These monoesters were treated with equimolar amounts of the corresponding pheophorbide by using benzotriazole-1-methanesulfonate/4-(dimethylamino)pyridine in CH2Cl2 or dicyclohexylcarbodiimide/4-(dimethylamino)pyridine in CH2Cl2 at ambient temperature.Yields of bis-(pheophorbide) ethylene glycol diesters averaged about 50percent for the former method and 70percent for the latter method.Insertion of the magnesium atoms into the a series macrocycles was accomplished with iodomagnesium 2,6-di-tert-butyl-4-methylphenolate, IMgBHT, in CH2Cl2, while the metalation of the b and bacterial series macrocycles was carried out with a mixture of IMgBHT and lithium 2,2,6,6-tetramethylpiperidie in thiophene, all at ambient temperature.Both mono- and dimethalated derivatives were isolated and characterized in each case.
