202409-75-4

Basic information

• Product Name: 2-chloro-3-[4-(methylsulfonyl)phenyl]-5-trifluoromethyl-pyridine
• Synonyms: 2-chloro-3-[4-(methylsulfonyl)phenyl]-5-trifluoromethyl-pyridine
• CAS NO: 202409-75-4
• Molecular Weight: 335.734
• Mol File: 202409-75-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-chloro-3-[4-(methylsulfonyl)phenyl]-5-trifluoromethyl-pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-3-[4-(methylsulfonyl)phenyl]-5-trifluoromethyl-pyridine(202409-75-4)
• EPA Substance Registry System: 2-chloro-3-[4-(methylsulfonyl)phenyl]-5-trifluoromethyl-pyridine(202409-75-4)

Safety Data

• Hazardous Substances Data: 202409-75-4(Hazardous Substances Data)

Upstream product

• 202409-74-3 2-amino-3-[4-(methylsulfonyl)phenyl]-5-trifluoromethyl-pyridine 
• 202409-73-2 2-amino-3-[4-(methylthio)phenyl]-5-trifluoromethyl-pyridine 
• 79456-30-7 3-bromo-5-trifluoromethyl-pyridin-2-ylamine 
• 74784-70-6 2-amino-5-trifluoromethylpyridine 
• 98546-51-1 (4-thiomethoxyphenyl)boronic acid 

Downstream Products

• 221297-53-6 3-[4-(methylsulfonyl)phenyl]-2-[4-(hydroxy)piperidin-1-yl]-5-trifluoromethyl-pyridine 
• 221296-81-7 3-[4-(methylsulfonyl)phenyl]-2-((2S)-2-(hydroxymethyl)pyrrolidin-1-yl)-5-trifluoromethyl-pyridine 

Relevant articles and documents

2-AMINOPYRIDINES AS INHIBITORS OF CYCLOOXYGENASE-2

The invention encompasses the novel compound of Formula (I) as well as a method of treating cyclooxygenase-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula (I). The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula (I).

2,3,5-trisubstituted pyridines as inhibitors of cyclooxygenase-2

The invention encompasses the novel compound of Formula I as well as a method of treating cyclooxygenase-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula I. STR1 The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula I.

Substituted pyridines as selective cyclooxygenase-2 inhibitors

The invention encompasses the novel compound of Formula I as well as a method of treating COX-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula I. STR1 The invention also encompasses certain pharmaceutical compositions for treatment of COX-2 mediated diseases comprising compounds of Formula I.