202464-95-7Relevant articles and documents
An efficient stereoselective synthesis of sphingosine
Kumar, Pradeep,Schmidt, Richard R.
, p. 33 - 35 (1998)
A stereocontrolled synthesis of D-(+)-erythro-sphingosine (1), starting from D-xylose as chiral pool material and employing the addition-fragmentation reaction of tosyl hydrazone of 2,3:4,5-di-O-isopropylidene-D-xylose as a key step for the chain extension with concomitant trans-selective C=C bond formation, is described.
Synthesis of an orthogonally protected d-(+)-erythro-sphingosine
Gargano, Joseph M.,Lees, Watson J.
, p. 5845 - 5847 (2007/10/03)
The synthesis presented provides rapid access to an orthogonally protected d-(+)-erythro-sphingosine: 1-methoxymethyl, 2-azido, 3-benzoyl. After selective deprotection the resulting sphingosine derivative is suitable for coupling to a wide variety of saccharides or other molecules at either the 1- or 3-position.