202533-73-1Relevant articles and documents
Conjugation of Small Molecules to RNA Using a Reducible Disulfide Linker Attached at the 2′-OH Position through a Carbamate Function
Gauthier, Florian,Malher, Astrid,Vasseur, Jean-Jacques,Dupouy, Christelle,Debart, Fran?oise
, p. 5636 - 5645 (2019)
A post-synthesis conjugation method was developed to functionalize oligoribonucleotides with various small molecules of biological interest using a reduction-sensitive disulfide linker connected to 2′OH via a carbamate function. For this, first we prepare
Chemical Synthesis and Properties of Conformationally Fixed Diuridine Monophosphates as Building Blocks of the RNA Turn Motif
Seio, Kohji,Wada, Takeshi,Sakamoto, Kensaku,Yokoyama, Shigeyuki,Sekine, Mitsuo
, p. 1429 - 1443 (2007/10/03)
Two intramolecularly cyclized diuridine monophosphates having an amide and a carbamate linker have been synthesized for fixation of the U-turn structure found in various tRNAs and hammerhead ribozymes. The structural analysis of these cyclic dimers using