202666-42-0Relevant articles and documents
Discovery of a novel series of selective MMP inhibitors: Identification of the γ-sulfone-thiols
Freskos, John N.,Mischke, Brent V.,DeCrescenzo, Gary A.,Heintz, Robert,Getman, Daniel P.,Howard, Susan C.,Kishore, Nandini N.,McDonald, Joseph J.,Munie, Grace E.,Rangwala, Shaukat,Swearingen, Craig A.,Voliva, Charles,Welsch, Dean J.
, p. 943 - 948 (1999)
We have discovered a new series of potent MMP inhibitors that are selective for MMP-13 over MMP-1 incorporating a γ-sulfone thiol.