20277-25-2

Basic information

• Product Name: Propanoic acid, 2,2-dimethyl-, 2-nitrophenyl ester
• CAS NO: 20277-25-2
• Molecular Formula: C11H13NO4
• Molecular Weight: 223.229
• Mol File: 20277-25-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Propanoic acid, 2,2-dimethyl-, 2-nitrophenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 2,2-dimethyl-, 2-nitrophenyl ester(20277-25-2)
• EPA Substance Registry System: Propanoic acid, 2,2-dimethyl-, 2-nitrophenyl ester(20277-25-2)

Safety Data

• Hazardous Substances Data: 20277-25-2(Hazardous Substances Data)

Upstream product

• 3282-30-2 pivaloyl chloride 
• 88-75-5 2-hydroxynitrobenzene 
• 4920-92-7 pivalic acid phenyl ester 

Relevant articles and documents

The elastase-catalyzed hydrolysis of p-nitrophenyl trimethylacetate.

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Ozone-mediated Reaction of Anilides and Phenyl Esters with Nitrogen Dioxide: Enhanced Ortho-reactivity and Mechanistic Implications

In the presence of ozone, anilides 1 can be nitrated rapidly with nitrogen dioxide in chloroform at 0 deg C to give a high proportion of ortho-nitro derivatives (ortho:para = 1.2-4.4) in good yields.The phenyl esters 15 can be similarly nitrated on the aromatic ring without significant cleavage of the ester bond, giving a mixture of isomeric nitro derivatives in which the ortho-isomer predominantes (ortho:para = 1.1-1.5).The oridin of the enhanced ortho reactivity is discussed in terms of an electron-transfer process involving the nitrogen trioxide as initial electrophile.