20287-70-1

Basic information

• Product Name: 2-(4-chlorophenyl)-4-thiazoleacetic acid ethyl ester
• Synonyms: 2-(4-chlorophenyl)-4-thiazoleacetic acid ethyl ester;ethyl 2-(2-(4-chlorophenyl)thiazol-4-yl)acetate;Ethyl fenclozate
• CAS NO: 20287-70-1
• Molecular Formula: C₁₃H₁₂ClNO₂S
• Molecular Weight: 281.76
• Mol File: 20287-70-1.mol
• Article Data: 10

Chemical Properties

• Melting Point: 114-116℃
• Boiling Point: 400.6°C at 760 mmHg
• Flash Point: 196.1°C
• Appearance: /
• Density: 1.288
• Vapor Pressure: 1.26E-06mmHg at 25°C
• Refractive Index: 1.58
• CAS DataBase Reference: 2-(4-chlorophenyl)-4-thiazoleacetic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-chlorophenyl)-4-thiazoleacetic acid ethyl ester(20287-70-1)
• EPA Substance Registry System: 2-(4-chlorophenyl)-4-thiazoleacetic acid ethyl ester(20287-70-1)

Safety Data

• Hazardous Substances Data: 20287-70-1(Hazardous Substances Data)

Usage

General Description

2-(4-chlorophenyl)-4-thiazoleacetic acid ethyl ester, also known as ethyl 2-(4-chlorophenyl)-4-thiazoleacetate, is a chemical compound with potential pharmaceutical applications. It belongs to the class of thiazole compounds, which have been studied for their antimicrobial, antifungal, and anti-inflammatory properties. This specific compound has been investigated for its potential use in developing new drugs for the treatment of various bacterial and fungal infections, as well as for its potential anti-inflammatory effects. Its ethyl ester form also suggests that it may have improved solubility and pharmacokinetic properties compared to the parent acid, making it a promising candidate for further pharmaceutical development.

InChI:InChI=1/C13H12ClNO2S/c1-2-17-12(16)7-11-8-18-13(15-11)9-3-5-10(14)6-4-9/h3-6,8H,2,7H2,1H3

Upstream product

• 638-07-3 ethyl (2-chloroaceto)acetate 
• 2521-24-6 4-chlorothiobenzamide 
• 64-17-5 ethanol 
• 32807-28-6 Methyl 4-chloroacetoacetate 
• 2521-24-6 4-chlorobenzothioamide 
• 1116-50-3 4-bromo-3-ethoxy-2-butenoic acid ethyl ester 
• 70-23-5 ethyl Bromopyruvate 

Downstream Products

• 58827-73-9 2-[2-(4-Chloro-phenyl)-thiazol-4-yl]-N-{2-[3-(2-cyano-phenoxy)-2-hydroxy-propylamino]-ethyl}-acetamide 
• 17969-36-7 2-[2-(4-chloro-phenyl)-thiazol-4-yl]-acetamide 
• 425381-87-9 ethyl 2-[2-(4-chlorophenyl)thiazol-4-yl]pent-4-enoate 
• 425381-74-4 3-[2-(4-chlorophenyl)thiazol-4-yl]-5-methyltetrahydrofuran-2-one 
• 425381-94-8 2-[2-(4-chlorophenyl)thiazol-4-yl]pent-4-enoic acid 
• 78743-13-2 3-[2-(4-Chloro-phenyl)-thiazol-4-yl]-4-hydroxy-pyrrole-2,5-dione 
• 27473-03-6 2-(2-(4-chlorophenyl)thiazol-4-yl)ethan-1-ol 
• 33313-15-4 [2-(4-chloro-phenyl)-thiazol-4-yl]-acetic acid hydrazide 
• 18832-93-4 2-(2-(4-chlorophenyl)thiazol-4-yl)acetonitrile 

Relevant articles and documents

PROCESS FOR PREPARING A POTENT THIAZOLE COMPOUND, PHARMACEUTICAL FORMULATION AND USES THEREOF

The present invention relates to a process for preparing N-[2-[2-(4-chlorophenyl)-4- thiazolyl] ethyl]-butanamide. The present invention further relates to a pharmaceutical formulation and the use of said pharmaceutical formulation consisting of N-[2-[2-(

Synthesis and Antimicrobial Screening of 2-Aryl-5-((2-arylthiazol-4-yl)methyl)-1,3,4-oxadiazole Derivatives

A new series of 2-aryl-5-((2-arylthiazol-4-yl)methyl)-1,3,4-oxadiazole derivatives was synthesized by condensation of 2-(2-substituted thiazol-4-yl)acetohydrazide with aryl aldehydes followed by oxidative cyclocondensation using iodobenzene diacetate. The

Synthesis and Antifungal Screening of 2-(2-Aryl-4-methyl-thiazol-5-yl)-5-((2-aryl/benzylthiazol-4-yl)methyl)-1,3,4-oxadiazole Derivatives

(Chemical Equation Presented) A new series of synthesis and biological screening of 2-(2-aryl-4-methyl-thiazol-5-yl)-5-((2-aryl/benzylthiazol-4-yl)methyl)-1,3,4-oxadiazole derivatives 5a-i was achieved by condensation of 2-(2-aryl/benzylthiazol-4-yl)aceto