20291-99-0 Usage
Description
Acetic acid, mercapto-, 1,1-dimethylethyl ester, also known as tert-Butyl 2-Sulfanylacetate, is an organic compound that features a mercapto group and an ester functional group. It is characterized by its unique chemical structure and properties, making it a versatile reagent in various chemical reactions and applications.
Uses
Used in Pharmaceutical Industry:
Acetic acid, mercapto-, 1,1-dimethylethyl ester is used as a reagent in the synthesis of enantiopure thioesters, such as (R)-2-(2-benzamidopropanoylthio)acetic. These enantiopure thioesters are key substrates for screening the sensitivity of penicillin binding proteins to inhibitors, which is crucial for the development of new antibiotics and understanding the mechanisms of action of existing ones.
Used in Chemical Synthesis:
In the field of chemical synthesis, Acetic acid, mercapto-, 1,1-dimethylethyl ester serves as a valuable intermediate for the preparation of various organic compounds. Its unique structure allows for selective reactions and transformations, making it a useful building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Research and Development:
Acetic acid, mercapto-, 1,1-dimethylethyl ester is also utilized in research and development settings to explore its potential applications and properties. Its reactivity and functional groups make it an interesting candidate for studying new reaction mechanisms, developing novel synthetic routes, and discovering new compounds with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 20291-99-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,2,9 and 1 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 20291-99:
(7*2)+(6*0)+(5*2)+(4*9)+(3*1)+(2*9)+(1*9)=90
90 % 10 = 0
So 20291-99-0 is a valid CAS Registry Number.
20291-99-0Relevant articles and documents
HETEROCYCLIC COMPOUNDS AS INHIBITORS OF KRAS G12C
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Page/Page column 103, (2021/01/23)
Provided are heterocyclic compounds as inhibitors of the KRAS G12C and uses thereof. Specifically, provided are the compounds of any of formula I to XI or stereoisomers, enantiomers, atropoisomerics or pharmaceutically acceptable salts thereof. Definition of each group in the formula can be found in the specification for details.
Novel sirtuin inhibitory warheads derived from the Nε-acetyl-lysine analog l-2-amino-7-carboxamidoheptanoic acid
He, Yanhua,Yan, Lingling,Zang, Wenwen,Zheng, Weiping
supporting information, p. 10442 - 10450 (2015/11/10)
Built upon the catalytic mechanism-based pan-SIRT1/2/3 inhibitory warhead l-2-amino-7-carboxamidoheptanoic acid (l-ACAH, a close structural analog of Nε-acetyl-lysine) that our laboratory discovered recently, in the current study, its carboxami
Evaluation of small-molecule modulators of the luteinizing hormone/choriogonadotropin and thyroid stimulating hormone receptors: Structure-activity relationships and selective binding patterns
Moore, Susanna,Jaeschke, Holger,Kleinau, Gunnar,Neumann, Susanne,Costanzi, Stefano,Jiang, Jian-Kang,Childress, John,Raaka, Bruce M.,Colson, Anny,Paschke, Ralf,Krause, Gerd,Thomas, Craig J.,Gershengorn, Marvin C.
, p. 3888 - 3896 (2007/10/03)
The substituted thieno[2,3-d]pyrimidine 3 (Org 41841), a partial agonist for the luteinizing hormone/choriogonadotropin receptor (LHCGR) and the closely related thyroid-stimulating hormone receptor (TSHR), was fundamentally altered, and the resulting anal
