203124-97-4

Basic information

• Product Name: Benzenepropanoic acid, a-[(methylsulfonyl)oxy]-, (S)-
• CAS NO: 203124-97-4
• Molecular Formula: C10H12O5S
• Molecular Weight: 244.268
• Mol File: 203124-97-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzenepropanoic acid, a-[(methylsulfonyl)oxy]-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanoic acid, a-[(methylsulfonyl)oxy]-, (S)-(203124-97-4)
• EPA Substance Registry System: Benzenepropanoic acid, a-[(methylsulfonyl)oxy]-, (S)-(203124-97-4)

Safety Data

• Hazardous Substances Data: 203124-97-4(Hazardous Substances Data)

Upstream product

• 135912-77-5 (S)-2-methanesulfonyloxy-3-phenylpropionic acid methyl ester 

Downstream Products

• 42990-55-6 (S)-(alpha)-bromobenzenepropanoic acid 

Relevant articles and documents

PROCESS FOR PRODUCING OPTICALLY ACTIVE 2-SUBSTITUTED CARBOXYLIC ACID

The present invention relates to a process for efficiently producing an optically active 2-bromocarboxylic acid and an optically active 2-sulfonyloxycarboxylic acid, which are important in the production of medicinal compounds and so forth. An optically active 2-sulfonyloxycarboxylic acid ester is subjected to deprotection under acid conditions to obtain an optically active 2-sulfonyloxycarboxylic acid. A metal bromide is caused to act on the acid to brominate it with configuration inversion at position 2 to thereby produce an optically active 2-bromocarboxylic acid. The resultant optically active 2-bromocarboxylic acid is isolated/purified by subjecting it to a step in which the acid is crystallized and separated as a salt with a base. Thus, an optically active 2-bromocarboxylic acid having a high chemical purity and high optical purity can be produced.