203453-89-8

Basic information

• Product Name: (4-isocyanato-cyclohexylmethyl)-carbamic acid 9H-fluoren-9-ylmethyl ester
• CAS NO: 203453-89-8
• Molecular Weight: 376.455
• Mol File: 203453-89-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-isocyanato-cyclohexylmethyl)-carbamic acid 9H-fluoren-9-ylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4-isocyanato-cyclohexylmethyl)-carbamic acid 9H-fluoren-9-ylmethyl ester(203453-89-8)
• EPA Substance Registry System: (4-isocyanato-cyclohexylmethyl)-carbamic acid 9H-fluoren-9-ylmethyl ester(203453-89-8)

Safety Data

• Hazardous Substances Data: 203453-89-8(Hazardous Substances Data)

Upstream product

• 167690-53-1 (1R,4R)-4-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclohexane-1-carboxylic acid 
• 82911-69-1 N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide 
• 1197-18-8 trans-4-aminomethyl-cyclohexyl-carboxylic acid 

Relevant articles and documents

High-throughput synthesis and optimization of thrombin inhibitors via urazole α-addition and Michael addition

A novel α-addition of propiolates to urazoles followed by Michael addition of a variety of nucleophiles has been developed for rapid production and optimization of peptidomimetic drug leads. This technology has produced a number of highly potent and selective inhibitors of the serine protease, thrombin.