203458-12-2

Basic information

• Product Name: C₁₇H₁₉NO₄S₂
• Synonyms: C₁₇H₁₉NO₄S₂
• CAS NO: 203458-12-2
• Molecular Weight: 365.474
• Mol File: 203458-12-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₇H₁₉NO₄S₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₁₉NO₄S₂(203458-12-2)
• EPA Substance Registry System: C₁₇H₁₉NO₄S₂(203458-12-2)

Safety Data

• Hazardous Substances Data: 203458-12-2(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 50487-71-3 4-methyl-N-(2-propenyl)benzenesulfonamide 

Downstream Products

• 140-67-0 Estragole 
• 768-56-9 4-Phenylbut-1-ene 

Relevant articles and documents

Cross-coupling of grignard reagents with sulfonyl-activated sp3 carbon-nitrogen bonds

Sulfonyl-activated sp3 carbon-nitrogen bonds have been found to be cleaved by Grignard reagents in the presence of 5 mol% of copper(I) iodide (CuI). Significantly, a broad range of sulfonyl-activated benzylic, allylic, and propargylic amines smoothly undergo the cross-coupling reaction with Grignard reagents to afford structurally diverse coupling products in good to excellent yields and with high chemo-, regio-, and stereoselectivity. Moreover, an S N2 mechanism has been demonstrated to be involved in the cross-coupling reaction that allows the asymmetric synthesis of chiral hydrocarbons from optically active α-branched amine derivatives. Copyright