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20348-21-4

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20348-21-4 Usage

General Description

2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one, also known as nicotine, is a highly toxic and addictive alkaloid compound found in tobacco plants. It is commonly consumed through smoking, chewing, or vaping, and acts as a stimulant on the central nervous system. Nicotine is known to increase the release of dopamine in the brain, leading to feelings of pleasure and euphoria. Prolonged use of nicotine can lead to addiction and a range of health problems, including cardiovascular disease, respiratory issues, and an increased risk of cancer. Due to its addictive nature and harmful effects on health, nicotine is closely regulated and its use is discouraged by health authorities.

Check Digit Verification of cas no

The CAS Registry Mumber 20348-21-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,3,4 and 8 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 20348-21:
(7*2)+(6*0)+(5*3)+(4*4)+(3*8)+(2*2)+(1*1)=74
74 % 10 = 4
So 20348-21-4 is a valid CAS Registry Number.
InChI:InChI=1/C9H10N2O2/c1-9(2)8(12)11-7-6(13-9)4-3-5-10-7/h3-5H,1-2H3,(H,10,11,12)

20348-21-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one

1.2 Other means of identification

Product number -
Other names 2,2-DIMETHOXYPROPIONIC ACID METHYL ESTER

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:20348-21-4 SDS

20348-21-4Relevant articles and documents

Preparation method of fostamatinib key intermediate and intermediate thereof and method for preparing fostamatinib with intermediate

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Paragraph 0053-0064, (2019/07/04)

The invention discloses a preparation method of a fostamatinib key intermediate and an intermediate thereof and a method for preparing fostamatinib with the intermediate. The preparation method of thefostamatinib key intermediate comprises the following steps: carrying out a nucleophilic substitution reaction on a compound (2) and a compound (3) so as to obtain a fostamatinib key intermediate compound (4), and carrying out reduction cyclization on the compound (4), thereby obtaining a fostamatinib key intermediate compound (1), wherein the reaction formula is as shown in the specification. The preparation method disclosed by the invention is easy in raw material and reagent obtaining, low in price, low in cost and easy in industrialization and has the advantages of being high in synthesisyield, good in product purity, and the like.

ALKYLIDINE SUBSTITUTED HETEROCYCLYL DERIVATIVES AS ANTI-BACTERIAL AGENTS

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Page/Page column 22, (2015/06/03)

The present invention relates to alkylidine substituted heterocyclyl derivatives of formula (1) which may be therapeutically useful as as anti-bacterial agents, more particulalrly FabI inhibitors; I in which P, Q, Ri, R2, R3 and "n" have the same meanings given in the specification, and pharmaceutically acceptable salts or pharmaceutically acceptable stereoisomers thereof that are useful in the treatment and prevention in diseases or disorder, in particular their use in diseases or disorder where there is an advantage in inhibiting Enoyl-ACP reductase enzyme (FABI) activity. The present invention also provides methods for synthesizing and administering the FabI inhibitory compounds. The present invention also provides pharmaceutical formulations comprising at least one of the FabI inhibitory compounds together with a pharmaceutically acceptable carrier, diluent or excipient therefor.

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