203508-62-7Relevant articles and documents
Stereoselective Palladium-Catalyzed Approach to Vitamin D3 Derivatives in Protic Medium
Carballa, Diego,Sigüeiro, Rita,Rodríguez-Docampo, Zaida,Zacconi, Flavia,Maestro, Miguel A.,Mouri?o, Antonio
, p. 3314 - 3320 (2018/02/12)
We describe an efficient convergent synthesis of vitamin D3 metabolites and analogues. The synthetic strategy relies on a tandem Pd-catalyzed A-ring closure and Suzuki–Miyaura coupling to the CD-side chain component to set directly the vitamin D triene system under protic conditions. This strategy enables rapid access to vitamin D3 and 3-epi-vitamin D3 metabolites and analogues modified at the side chain for biological evaluation and structural and metabolic studies.
SOLID FORMS OF 2-(TERT-BUTYLAMINO)-4-((1R,3R,4R)-3-HYDROXY-4-METHYLCYCLOHEXYLAMINO)-PYRIMIDINE-5-CARBOXAMIDE, COMPOSITIONS THEREOF AND METHODS OF THEIR USE
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Paragraph 00452, (2015/11/02)
Provided herein are formulations, processes, solid forms and methods of use relating to 2- (tert-butylamino)-4-((lR,3R,4R)-3-hydroxy-4-methylcyclohexylamino)-pyrimidine-5- carboxamide.
Synthesis and absolute configuration of rotundial, a mosquito repellent from the leaves of vitex rotundiforia
Takikawa, Hirosato,Yamazaki, Yuichiro,Mori, Kenji
, p. 229 - 232 (2007/10/03)
The enantiomers of rotundial (1), a mosquito repellent from the leaves of Vitex rotundiforia, were synthesized from the enantiomers of limonene oxide (2). The absolute configuration of natural rotundial was determined to be R.