203576-39-0

Basic information

• Product Name: (4S,5S)-4-hydroxymethyl-2-methyl-5-[4-(methylthio)phenyl]-2-oxazoline
• Synonyms: (4S,5S)-4-hydroxymethyl-2-methyl-5-[4-(methylthio)phenyl]-2-oxazoline
• CAS NO: 203576-39-0
• Molecular Weight: 237.323
• Mol File: 203576-39-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (4S,5S)-4-hydroxymethyl-2-methyl-5-[4-(methylthio)phenyl]-2-oxazoline(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,5S)-4-hydroxymethyl-2-methyl-5-[4-(methylthio)phenyl]-2-oxazoline(203576-39-0)
• EPA Substance Registry System: (4S,5S)-4-hydroxymethyl-2-methyl-5-[4-(methylthio)phenyl]-2-oxazoline(203576-39-0)

Safety Data

• Hazardous Substances Data: 203576-39-0(Hazardous Substances Data)

Upstream product

• 16854-32-3 (1S,2S)-(+)-thiomicamine 
• 2208-07-3 ethyl acetimidate hydrochloride 
• 75-05-8 acetonitrile 
• 78-39-7 Triethyl orthoacetate 

Downstream Products

• 914477-57-9 (4S,5S)-2-methyl-4-mesyloxymethyl-5-(4-methylsulfanylphenyl)-oxazoline 
• 203576-40-3 (4S,5S)-4-methoxymethyl-2-methyl-5-(4-methylthiophenyl)-4,5-dihydro-1,3-oxazole 

Relevant articles and documents

Modular synthesis of chiral pentadentate bis(oxazoline) ligands

Highly modular N,Y,Z,Y,N-ligands (Y=N, O, S; Z=N, NO, OH, OMe) have been prepared using bis(oxazoline) building blocks either as nucleophiles or as electrophiles in coupling reactions with central aromatic units. This way, a great variety of pentadentate

Asymmetric conjugate addition reaction

This invention relates to a key intermediate in the synthesis of an endothelin antagonist the synthesis of this key intermediate via an asymmetric conjugate addition reaction.