203789-94-0

Basic information

• Product Name: N-Boc-N-(tert-butyloxycarbonylmethylene)-(D)-cyclohexylalanine benzyl ester
• Synonyms: N-Boc-N-(tert-butyloxycarbonylmethylene)-(D)-cyclohexylalanine benzyl ester
• CAS NO: 203789-94-0
• Molecular Weight: 475.626
• Mol File: 203789-94-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-Boc-N-(tert-butyloxycarbonylmethylene)-(D)-cyclohexylalanine benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-Boc-N-(tert-butyloxycarbonylmethylene)-(D)-cyclohexylalanine benzyl ester(203789-94-0)
• EPA Substance Registry System: N-Boc-N-(tert-butyloxycarbonylmethylene)-(D)-cyclohexylalanine benzyl ester(203789-94-0)

Safety Data

• Hazardous Substances Data: 203789-94-0(Hazardous Substances Data)

Upstream product

• 203789-93-9 N-(tert-butyloxycarbonylmethylene)-(D)-cyclohexylalanine benzyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 100-51-6 benzyl alcohol 
• 58717-02-5 3-cyclohexyl-D-alanine 
• 5292-43-3 bromoacetic acid tert-butyl ester 

Downstream Products

• 190904-21-3 (2R)-2-[(tert-butoxycarbonyl)(2-tert-butoxy-2-oxoethyl)amino]-3-cyclohexylpropanoic acid 

Relevant articles and documents

Orally active thrombin inhibitors. Part 1: Optimization of the P1-moiety

The synthesis and SAR of novel nanomolar thrombin inhibitors with the common backbone HOOC-CH2-d-cyclohexylalanyl-3,4-dehydroprolyl-NH-CH 2-aryl-C(double bond, long NH)NH2 are described together with their ecarin clotting

Thrombin inhibitors

Novel five-membered heterocyclic amidines, their preparation and use as competitive inhibitors of trypsin-like serine proteases, especially thrombin and kininogenases such as kallikrein. Pharmaceutical compositions which contain the compounds as active ingredients, and use of the compounds as thrombin inhibitors, anticoagulants and antiinflammatory agents.