20380-17-0Relevant articles and documents
Efficient Synthesis of the Corticosteroid Side-chain from 17-Ketones
Barton, Derek H. R.,Motherwell, William B.,Zard, Samir Z.
, p. 774 - 775 (1981)
Steroidal 17-ketones react smoothly with diethyl α-isocyanoethyl phosphonate to give, after suitable oxidative and hydrolytic reactions, the dihydroxy-acetone side-chain of corticosteroids in high yield.
Process for the preparation of 21-bromo-4-pregnene-3,20-dione derivatives
-
, (2008/06/13)
A process is disclosed for the preparation of 21-bromo-4-pregnene-3,20-dione derivatives of general Formula I STR1 wherein R1 is a hydrogen atom, a hydroxy group or an alkanoyl group of up to 6 carbon atoms, R2 symbolizes a hydrogen atom or a methyl group, or wherein R1 and R2 jointly mean an isopropylidenedioxy group, wherein R3 is a hydrogen atom, a fluorine atom or a methyl group, V is a methylene group or ethylene group, X is a hydrogen atom, a fluorine atom or a chlorine atom, and Y is a methylene group, a hydroxymethylene group or a carbonyl group.
SYNTHESIS OF THE 21-ACETATE OF SUBSTANCE S FROM 17α-HYDROXYPROGESTERONE
Ryakhovskaya, M. I.,Popova, E. V.,Andryushina, V. A.,Grinenko, G. S.
, p. 839 - 842 (2007/10/02)
-