20386-34-9 Usage
Description
[4-(2-chlorophenyl)piperazin-1-yl](phenyl)methanone is a piperazine derivative featuring a piperazine ring with a 2-chlorophenyl group and a phenylmethanone group attached. This chemical compound serves as a pharmaceutical intermediate and holds potential for psychoactive effects due to its structural resemblance to other psychoactive substances. Its unique chemical structure and properties render it a valuable starting material for the synthesis of a variety of pharmacologically active compounds, particularly those targeting central nervous system disorders.
Uses
Used in Pharmaceutical Industry:
[4-(2-chlorophenyl)piperazin-1-yl](phenyl)methanone is used as a pharmaceutical intermediate for the synthesis of various medications. Its unique structure allows for the development of diverse pharmacologically active compounds, contributing to the creation of new treatments for a range of medical conditions.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, [4-(2-chlorophenyl)piperazin-1-yl](phenyl)methanone is utilized for the development of new drugs targeting central nervous system disorders. Its structural similarity to psychoactive substances makes it a promising candidate for designing novel therapeutic agents to address various neurological and psychiatric conditions.
Used in Psychoactive Substance Research:
Due to its potential psychoactive effects, [4-(2-chlorophenyl)piperazin-1-yl](phenyl)methanone is also used in research aimed at understanding the mechanisms of action and potential applications of psychoactive substances. This research can lead to the development of new treatments for conditions such as anxiety, depression, and other mood disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 20386-34-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,3,8 and 6 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 20386-34:
(7*2)+(6*0)+(5*3)+(4*8)+(3*6)+(2*3)+(1*4)=89
89 % 10 = 9
So 20386-34-9 is a valid CAS Registry Number.
20386-34-9Relevant articles and documents
Synthesis of ortho -haloaminoarenes by aryne insertion of nitrogen-halide Bonds
Hendrick, Charles E.,Wang, Qiu
, p. 1059 - 1069 (2015/01/30)
A rapid and general access to ortho-haloaminoarenes has been developed by aryne insertion into N-chloramine, N-bromoamine, and N-iodoamine bonds via two complementary protocols harnessing fluoride-promoted 1,2-elimination of ortho-trimethylsilyl aryltriflates. Typically, electron-deficient N-chloramines effectively react with aryne intermediates generated at elevated temperature with CsF, while less stable N-haloamines are found more efficient under milder, TBAF-mediated aryne formation at room temperature. Both protocols demonstrate a good level of regioselectivity and functional group tolerance. Efforts to elucidate the mechanism of N-X insertion are also discussed. The practical value of this transformation is highlighted by rapid synthesis of novel analogues of the antipsychotic cariprazine.
New analgetic agents. V. 1-butyryl-4-cinnamylpiperazine hydrochloride and related compounds.
Irikura,Masuzawa,Nishino,Kitagawa,Uchida,Ichinoseki,Ito
, p. 801 - 804 (2007/10/04)
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