204067-75-4Relevant articles and documents
Synthesis and biological activity of a novel squalene epoxidase inhibitor, FR194738
Sawada, Masae,Washizuka, Ken-Ichi,Okumura, Hiroyuki
, p. 633 - 637 (2007/10/03)
The synthesis and biological properties of a novel squalene epoxidase inhibitor, FR194738, are described. This compound displayed potent in vitro inhibitory activities against squalene epoxidase and cholesterol synthesis, and lowered plasma cholesterol and triglyceride levels in dogs.