204254-79-5 Usage
Description
Ethyl (3aR,5R,7R,7aS)-5,7-dihydroxy-2,2-dimethylhexahydro-benzo[1,3]dioxole-5-carboxylate is a complex organic compound with a unique molecular structure. It is characterized by its hexahydro-benzo[1,3]dioxole core, which features two methyl groups and a carboxylate ester group. ethyl (3aR,5R,7R,7aS)-5,7-dihydroxy-2,2-dimethylhexahydro-benzo[1,3]dioxole-5-carboxylate is known for its chiral centers, with the specific configuration of 3aR,5R,7R,7aS, which contributes to its distinct properties and potential applications.
Used in Pharmaceutical Industry:
Ethyl (3aR,5R,7R,7aS)-5,7-dihydroxy-2,2-dimethylhexahydro-benzo[1,3]dioxole-5-carboxylate is used as a key intermediate in the synthesis of anti-influenza drugs, specifically for the development of GS-4104. ethyl (3aR,5R,7R,7aS)-5,7-dihydroxy-2,2-dimethylhexahydro-benzo[1,3]dioxole-5-carboxylate plays a crucial role in the production of effective medications that combat influenza viruses, offering a valuable contribution to public health and disease management. Its unique structure and properties make it an essential component in the creation of innovative pharmaceuticals targeting viral infections.
Check Digit Verification of cas no
The CAS Registry Mumber 204254-79-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,4,2,5 and 4 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 204254-79:
(8*2)+(7*0)+(6*4)+(5*2)+(4*5)+(3*4)+(2*7)+(1*9)=105
105 % 10 = 5
So 204254-79-5 is a valid CAS Registry Number.
204254-79-5Relevant articles and documents
Synthesis of p-coumaroylquinic acids and analysis of their interconversion
Gutiérrez Ortiz, Anggy Lusanna,Berti, Federico,Navarini, Luciano,Monteiro, Angelo,Resmini, Marina,Forzato, Cristina
, p. 419 - 427 (2017/03/23)
The synthesis of four isomers of p-coumaroylquinic acids was performed by esterification of p-acetylcoumaroylchloride with a suitably protected (?)-quinic acid. All isomers have been characterized by means of NMR spectroscopy and circular dichroism. Acyl migration was observed in the synthesis of 3-O-p-coumaroylquinic acid and 4-O-p-coumaroylquinic acid. Calculations on the most stable conformations of all isomers have also been performed to explain the acyl migration observed during the synthesis procedure.
Syntheses of 3-, 4-, and 5-O-feruloylquinic acids
Dokli, Irena,Navarini, Luciano,Hamersak, Zdenko
, p. 785 - 790 (2013/08/23)
The efficient synthesis of 3-, 4-, and 5-O-feruloylquinic acids starting from d-(-)-quinic acid is described. Esterification of suitably protected quinic acid derivatives with 3-(4-acetoxy-3-methoxyphenyl)-acryloyl chloride and subsequent hydrolysis of al
Practical Total Synthesis of the Anti-Influenza Drug GS-4104
Rohloff, John C.,Kent, Kenneth M.,Postich, Michael J.,Becker, Mark W.,Chapman, Harlan H.,Kelly, Daphne E.,Lew, Willard,Louie, Michael S.,McGee, Lawrence R.,Prisbe, Ernest J.,Schultze, Lisa M.,Yu, Richard H.,Zhang, Lijun
, p. 4545 - 4547 (2007/10/03)
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