204381-51-1

Basic information

• Product Name: tert-butyl 3-(benzoyloxy)pyrrolidine-1-carboxylate
• Synonyms: tert-butyl 3-(benzoyloxy)pyrrolidine-1-carboxylate
• CAS NO: 204381-51-1
• Molecular Weight: 291.347
• Mol File: 204381-51-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: tert-butyl 3-(benzoyloxy)pyrrolidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 3-(benzoyloxy)pyrrolidine-1-carboxylate(204381-51-1)
• EPA Substance Registry System: tert-butyl 3-(benzoyloxy)pyrrolidine-1-carboxylate(204381-51-1)

Safety Data

• Hazardous Substances Data: 204381-51-1(Hazardous Substances Data)

Upstream product

• 103057-44-9 N-(tert-butoxycarbonyl)-3-hydroxypyrrolidine 
• 65-85-0 benzoic acid 
• 98-88-4 benzoyl chloride 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 204381-53-3 Benzoic acid 1-((S)-2-tert-butoxycarbonylamino-3-phenyl-propionyl)-pyrrolidin-3-yl ester 
• 51285-23-5 benzoic acid pirrolidin-3-yl ester 

Relevant articles and documents

Development of a redox-free Mitsunobu reaction exploiting phosphine oxides as precursors to dioxyphosphoranes

The development of the first redox-free protocol for the Mitsunobu reaction is described. This has been achieved by exploiting triphenylphosphine oxide-the unwanted by-product in the conventional Mitsunobu reaction-as the precursor to the active P(v) coupling reagent. Multinuclear NMR studies are consistent with hydroxyl activation via an alkoxyphosphonium salt.