20444-00-2Relevant articles and documents
1-(2,6-Dichlorophenyl)ethylamine: A new and efficient chiral auxiliary for the Staudinger β-lactam synthesis
Hashimoto, Yukihiko,Kai, Akiyoshi,Saigo, Kazuhiko
, p. 8821 - 8824 (2007/10/02)
The diastereoselective synthesis of β-lactams by the Staudinger reaction was examined using chiral imines, derived from substituted 1-phenylethylamines. Among them, 1-(2,6-dichlorophenyl)ethylamine was found to be a new and efficient chiral auxiliary, and the corresponding cis-β-lactams were obtained in good to excellent yields with high diastereoselectivity.