204444-52-0

Basic information

• Product Name: 4-bromo-2-methyl-5-nitro-1-phenacylimidazole
• Synonyms: 4-bromo-2-methyl-5-nitro-1-phenacylimidazole
• CAS NO: 204444-52-0
• Molecular Weight: 324.134
• Mol File: 204444-52-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-bromo-2-methyl-5-nitro-1-phenacylimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-2-methyl-5-nitro-1-phenacylimidazole(204444-52-0)
• EPA Substance Registry System: 4-bromo-2-methyl-5-nitro-1-phenacylimidazole(204444-52-0)

Safety Data

• Hazardous Substances Data: 204444-52-0(Hazardous Substances Data)

Upstream product

• 70-11-1 α-bromoacetophenone 
• 18874-52-7 5-bromo-2-methyl-4-nitro-1H-imidazole 
• 18874-52-7 4-bromo-2-methyl-5-nitroimidazole 

Downstream Products

• 57338-58-6 5-bromo-1-phenacyl-2-methyl-4-nitroimidazole 

Relevant articles and documents

NOVEL DERIVATIVES OF IMIDAZOLE, USE OF NOVEL DERIVATIVES OF IMIDAZOLE AND A METHOD OF MANUFACTURING THEM

Novel derivatives of imidazole, a method of manufacturing them as well as their use as the active substance in medicinal products for use in human and veterinary medicine have been disclosed.

Tetrabutyl ammonium bromide as a catalyst for reaction of 5(4)-bromo-2-methyl-4(5)-nitroimidazole with phenacyl bromides

Reactions of 5(4)-bromo-2-methyl-4(5)-nitroimidazole with phenacyl bromide, tetrabutylammonium bromide (TBAB) and sodium bicarbonate in the sonication condition resulted in a mixture of 4-bromo-5-nitroimidazoles [IIIa-e] and 5-bromo-4-nitroimidazoles [IVa-e] at an excellent yield of over 85% and, surprisingly, at the isomers ratio of 2:1.