204444-54-2

Basic information

• Product Name: 4-bromo-1-(4'-chlorophenacyl)-2-methyl-5-nitroimidazole
• Synonyms: 4-bromo-1-(4'-chlorophenacyl)-2-methyl-5-nitroimidazole
• CAS NO: 204444-54-2
• Molecular Weight: 358.579
• Mol File: 204444-54-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-bromo-1-(4'-chlorophenacyl)-2-methyl-5-nitroimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-1-(4'-chlorophenacyl)-2-methyl-5-nitroimidazole(204444-54-2)
• EPA Substance Registry System: 4-bromo-1-(4'-chlorophenacyl)-2-methyl-5-nitroimidazole(204444-54-2)

Safety Data

• Hazardous Substances Data: 204444-54-2(Hazardous Substances Data)

Upstream product

• 536-38-9 4-chlorobenzoylmethyl bromide 
• 18874-52-7 5-bromo-2-methyl-4-nitro-1H-imidazole 
• 18874-52-7 4-bromo-2-methyl-5-nitroimidazole 

Downstream Products

• 57338-59-7 5-bromo-1-(4'-chlorophenacyl)-2-methyl-4-nitroimidazole 

Relevant articles and documents

A convenient approach to the synthesis of the imidazo[5,1-b]oxazole ring system

Reaction of 4(5)-bromo-2-methyl-5(4)-nitroimidazole with phenacyl bromide derivatives led to 4-bromo-2-methyl-1-phenacyl-5-nitro- and 5-bromo- 2-methyl-1-phenacyl-4-nitroimidazoles. Treatment of the latter isomers with potassium tert-butoxide in dry THF y

Synthesis of some 5-amino-2-methyl-4-nitro-1-phenacylimidazoles

Reaction of 4(5)-bromo-2-methyl-5(4)-nitroimidazole with phenacyl bromide derivatives gave two isomers: 4-bromo-5-nitroimidazoles (4a-e) and 5-bromo-4-nitroimidazoles (5a-e). Compounds 5a-e were treated with cyclic secondary amines to afford expected 5-amino-4-nitroimidazole derivatives 6a-c - 10a-b.