204458-18-4

Basic information

• Product Name: Pyridine, 5-chloro-2-(phenylsulfonyl)-
• CAS NO: 204458-18-4
• Molecular Formula: C11H8ClNO2S
• Molecular Weight: 253.709
• Mol File: 204458-18-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Pyridine, 5-chloro-2-(phenylsulfonyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 5-chloro-2-(phenylsulfonyl)-(204458-18-4)
• EPA Substance Registry System: Pyridine, 5-chloro-2-(phenylsulfonyl)-(204458-18-4)

Safety Data

• Hazardous Substances Data: 204458-18-4(Hazardous Substances Data)

Upstream product

• 53175-28-3 2-chloro-2-butenal 
• 49805-26-7 benzenesulfonyl cyanide 
• 688-74-4 boric acid tributyl ester 
• 25129-61-7 α-chlorocrotonaldehyde 
• 24224-99-5 benzenesulfonyl cyanide 
• 594847-75-3 5-chloro-2-(phenylthio)pyridine 

Downstream Products

• 594847-72-0 phenyl 5-(1-piperazinyl)-2-pyridinyl sulfone 

Relevant articles and documents

Pyridyl sulfone derivatives

The invention provides compounds of the formula and methods of using those compounds for treating a disease or condition in a mammal wherein a 5-HT receptor, such as a 5-HT6 receptor, is implicated and modulation of a 5-HT function is desired, wherein A, G and W1-W3 are defined as herein.

Method for producing 2-sulfonylpyridine derivatives and method for producing 2-{[(2-pyridyl)methyl]thio}-1H-benzimidazole derivatives

2-Sulfonylpyridine derivatives can be industrially produced efficiently by reacting a sulfonyl cyanide derivative with an α, β-unsaturated carbonyl compound and a 2-{[(2-pyridyl)methyl]thio}-1H-benzimidazole skeleton can be formed in one step in a good yield by reacting this type of the 2-sulfonylpyridine derivative with a 2-methylthio-1H-benzimidazole derivative in the presence of an organolithium compound.