2044709-83-1

Basic information

• Product Name: N-Me-D-Asp(OtBu)-OH
• Synonyms: N-Me-D-Asp(OtBu)-OH
• CAS NO: 2044709-83-1
• Molecular Formula: C9H17NO4
• Molecular Weight: 203.24
• Product Categories: amino acids
• Mol File: 2044709-83-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-Me-D-Asp(OtBu)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: N-Me-D-Asp(OtBu)-OH(2044709-83-1)
• EPA Substance Registry System: N-Me-D-Asp(OtBu)-OH(2044709-83-1)

Safety Data

• Hazardous Substances Data: 2044709-83-1(Hazardous Substances Data)

Downstream Products

• 197632-85-2 N-Me-Asp(OtBu)-OH 

Relevant articles and documents

Synthesis method of N-methyl-(2S)-2-N-fluorenylmethoxycarbonylamino-aspartic acid (4-tert-butyl ester)

The invention relates to a synthesis method of N-methyl-(2S)-2-N-fluorenylmethoxycarbonyl amino-aspartic acid (4-tert-butyl ester). The method mainly solves the technical problem of product racemization and the problem of large-scale production in the existing synthesis method. The preparation method comprises the following four steps: step 1, dissolving a raw material A in tetrahydrofuran, addingcesium carbonate and methyl iodide to obtain a compound 1, and directly applying the product to the next step of reaction without purification; 2, at room temperature, introducing hydrogen into the compound 1 to react in methanol, and carrying out palladium-carbon catalysis to obtain a compound 2; 3, dissolving the compound 2 in methyl alcohol, adding L-(-)-diacetyl tartaric acid, and carrying out salifying treatment until ee is larger than 99%, so that a compound 3 is obtained, 4, performing a reaction on the compound 3 with acetone and sodium hydroxide, adding Fmoc-OSu is added for a reaction, and performing hydrochloric acid acidification to obtain the target compound 4.