204511-59-1

Basic information

• Product Name: [(2-Fluoro-phenyl)-hydrazono]-(1H-indol-3-yl)-acetic acid ethyl ester
• CAS NO: 204511-59-1
• Molecular Weight: 325.342
• Mol File: 204511-59-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [(2-Fluoro-phenyl)-hydrazono]-(1H-indol-3-yl)-acetic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [(2-Fluoro-phenyl)-hydrazono]-(1H-indol-3-yl)-acetic acid ethyl ester(204511-59-1)
• EPA Substance Registry System: [(2-Fluoro-phenyl)-hydrazono]-(1H-indol-3-yl)-acetic acid ethyl ester(204511-59-1)

Safety Data

• Hazardous Substances Data: 204511-59-1(Hazardous Substances Data)

Upstream product

• 120-72-9 indole 
• 51079-10-8 ethyl 2-(1H-indol-3-yl)-2-oxoacetate 
• 2368-80-1 2-fluorophenylhydrazine 

Relevant articles and documents

Tricyclic heteroaromatic systems. Pyrazolo[3,4-c]quinolin-4-ones and pyrazolo[3,4-c]quinoline-1,4-diones: Synthesis and benzodiazepine receptor activity

Some pyrazolo[3,4-c]quinoline-4-ones 1-14 and pyrazolo[3,4-c]-quinoline-1,4-diones 15-17 were prepared and biologically evaluated for their binding at the benzodiazepine receptor (BZR) in rat cortical membranes. The moderate binding activity of 1-5, 7, 9-10, 13 is attributable to the lack of the optional proton acceptor at position-1, while the inactivity of the 1,4-dione derivatives 15-17 is due to the lack of the essential proton acceptor at position-3. These conclusions confirm the validity of our proposed pharmacophoric model.