204845-95-4

Basic information

• Product Name: 6-(Benzyloxy)-9-[(1S,3R,4S)-2-methylene-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]cyclopentyl]-9H-purine-2-amine
• Synonyms: 6-(Benzyloxy)-9-(1S,3R,4S)-4-(benzyloxy)-3-(benzyoxymethyl)-2-methylenecyclopentyl)-9H-purin-2-amine;6-(Benzyloxy)-9-[(1S,3R,4S)-2-methylene-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]cyclopentyl]-9H-purine-2-amine;9H-Purine-2-amine, 9-[(1S, 3R, 4S)-2-methylene-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]cyclopentyl]-6-(phenylmethoxy);6-(benzyloxy)-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-Methylenecyclopentyl]-9H-purin-2-amine;Entecavir-8;Entecavir InterMediate VIII;6-(Benzyloxy)-9-[(1S,3R,4S)-2-Methylene-4-(phenylMethoxy)-3-[(phenylMethoxy)Methyl]cyclopentyl]-9H-p;6-(Benzyloxy)-9-((1S,3R,4S)-4-(benzyloxy)-3-((benzyloxy)-methyl)-2-methylenecyclopentyl)-9H-purin
• CAS NO: 204845-95-4
• Molecular Formula: C33H33N5O3
• Molecular Weight: 547.65
• Mol File: 204845-95-4.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 750.8 °C at 760 mmHg
• Flash Point: 407.8 °C
• Appearance: /
• Density: 1.26
• Refractive Index: 1.653
• Storage Temp.: 2-8°C
• PKA: 3.07±0.10(Predicted)
• CAS DataBase Reference: 6-(Benzyloxy)-9-[(1S,3R,4S)-2-methylene-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]cyclopentyl]-9H-purine-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(Benzyloxy)-9-[(1S,3R,4S)-2-methylene-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]cyclopentyl]-9H-purine-2-amine(204845-95-4)
• EPA Substance Registry System: 6-(Benzyloxy)-9-[(1S,3R,4S)-2-methylene-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]cyclopentyl]-9H-purine-2-amine(204845-95-4)

Safety Data

• Hazardous Substances Data: 204845-95-4(Hazardous Substances Data)

Usage

Description

6-(Benzyloxy)-9-[(1S,3R,4S)-2-methylene-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]cyclopentyl]-9H-purine-2-amine is a complex organic compound with a unique molecular structure. It is characterized by its benzyloxy and phenylmethoxy groups, as well as its cyclopentyl and purine-2-amine moieties. 6-(Benzyloxy)-9-[(1S,3R,4S)-2-methylene-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]cyclopentyl]-9H-purine-2-amine has potential applications in various fields due to its unique chemical properties and interactions with other molecules.

Uses

1. Pharmaceutical Industry:
6-(Benzyloxy)-9-[(1S,3R,4S)-2-methylene-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]cyclopentyl]-9H-purine-2-amine is used as an intermediate in the synthesis of antiviral agents, specifically for the preparation of Entecavir (E558900). Entecavir is a nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat chronic hepatitis B virus (HBV) infection.
2. Research and Development:
6-(Benzyloxy)-9-[(1S,3R,4S)-2-methylene-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]cyclopentyl]-9H-purine-2-amine may also be used in research and development for the discovery of new pharmaceuticals and therapeutic agents. Its unique structure and functional groups can be exploited to design and synthesize novel molecules with potential applications in various therapeutic areas.
3. Chemical Synthesis:
6-(Benzyloxy)-9-[(1S,3R,4S)-2-methylene-4-(phenylmethoxy)-3-[(phenylmethoxy)methyl]cyclopentyl]-9H-purine-2-amine can be used as a building block or starting material in the synthesis of more complex organic molecules, particularly in the fields of medicinal chemistry and drug discovery.

InChI:InChI=1/C33H33N5O3/c1-23-27(21-39-18-24-11-5-2-6-12-24)29(40-19-25-13-7-3-8-14-25)17-28(23)38-22-35-30-31(38)36-33(34)37-32(30)41-20-26-15-9-4-10-16-26/h2-16,22,27-29H,1,17-21H2,(H2,34,36,37)/t27-,28-,29-/m0/s1