20489-54-7Relevant articles and documents
Cobalt-Catalyzed Cross-Coupling of Functionalized Alkylzinc Reagents with (Hetero)Aryl Halides
Grokenberger, Lucie,Hammann, Jeffrey M.,Karaghiosoff, Konstantin,Knochel, Paul,Lutter, Ferdinand H.,Spie?, Philipp
supporting information, p. 5546 - 5550 (2020/02/26)
A combination of 10 % CoCl2 and 20 % 2,2′-bipyridine ligands enables cross-coupling of functionalized primary and secondary alkylzinc reagents with various (hetero)aryl halides. Couplings with 1,3- and 1,4-substituted cycloalkylzinc reagents proceeded diastereoselectively leading to functionalized heterocycles with high diastereoselectivities of up to 98:2. Furthermore, alkynyl bromides react with primary and secondary alkylzinc reagents providing the alkylated alkynes.
Hydrogenation selectivity of the Bicyclo[4.4.0]decane ring system of valencanes
Sauer, Anne M.,Crowe, William E.,Henderson, Gregg,Laine, Roger A.
scheme or table, p. 445 - 448 (2010/04/26)
To test the selectivity of sterically hindered systems, (+)-nootkatone and derivatives were subjected to a wide variety of hydrogenation methodologies. The steric impact of the C-4 methyl substituent seems to be responsible for the inability of the system to adopt the cis-fused structure. Georg Thieme Verlag Stuttgart New York.
Structure and absolute configuration of kusunol.
Hikino,Suzuki,Takemoto
, p. 832 - 838 (2007/10/05)
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