204929-66-8

Basic information

• Product Name: (2R,5S,6S)-7-Ethoxycarbonyl-6-tert-butoxycarbonylmethyl-8-oxo-2-phenyl-3-oxa-1-azabicyclo[3.3.0]octane
• Synonyms: (2R,5S,6S)-7-Ethoxycarbonyl-6-tert-butoxycarbonylmethyl-8-oxo-2-phenyl-3-oxa-1-azabicyclo[3.3.0]octane
• CAS NO: 204929-66-8
• Molecular Weight: 389.448
• Mol File: 204929-66-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,5S,6S)-7-Ethoxycarbonyl-6-tert-butoxycarbonylmethyl-8-oxo-2-phenyl-3-oxa-1-azabicyclo[3.3.0]octane(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,5S,6S)-7-Ethoxycarbonyl-6-tert-butoxycarbonylmethyl-8-oxo-2-phenyl-3-oxa-1-azabicyclo[3.3.0]octane(204929-66-8)
• EPA Substance Registry System: (2R,5S,6S)-7-Ethoxycarbonyl-6-tert-butoxycarbonylmethyl-8-oxo-2-phenyl-3-oxa-1-azabicyclo[3.3.0]octane(204929-66-8)

Safety Data

• Hazardous Substances Data: 204929-66-8(Hazardous Substances Data)

Upstream product

• 5292-43-3 bromoacetic acid tert-butyl ester 
• 166765-36-2 (2R,5S)-7-ethoxycarbonyl-8-oxo-2-phenyl-1-aza-3-oxa-bicyclo[3.3.0]oct-6-ene 

Downstream Products

• 303149-84-0 (2R,5S,6R)-6-tert-Butoxycarbonylmethyl-8-oxo-2-phenyl-3-oxa-1-azabicyclo[3.3.0]octane 
• 204929-81-7 (2S,3S,4R)-4-Benzyl-3-tert-butoxycarbonylmethyl-4-ethoxycarbonyl-2-hydroxymethyl-5-oxopyrrolidine 
• 204929-80-6 (2S,3S,4S)-4-Benzyl-3-tert-butoxycarbonylmethyl-4-ethoxycarbonyl-2-hydroxymethyl-5-oxopyrrolidine 
• 204929-82-8 (2S,3S,4S)-4-Benzyl-3-tert-butoxycarbonylmethyl-4-carboxy-2-hydroxymethyl-5-oxopyrrolidine 
• 885477-47-4 7-tert-butoxycarbonylmethyl-6-[2-methoxy-4-(3-trifluoromethyl-3H-diazirin-3-yl)-benzyl]-5-oxo-3-phenyl-tetrahydro-pyrrolo[1,2-c]oxazole-6-carboxylic acid ethyl ester 

Relevant articles and documents

Direct versatile route to conformationally constrained glutamate analogues

Novel conformationally constrained glutamate analogues are readily available from (S)-pyroglutamic acid; using a bicyclic lactam template, diastereocontrolled and sequential modification of the pyrrolidine ring is possible, allowing a versatile access to several glutamate and kainoid analogues; variations in the C(2)H-C(3)H coupling constants were observed depending upon the nature of remote substituents on the heterocyclic ring, consistent with modification of the ring conformation.