205171-12-6 Usage
Description
2'-MeCCPA, also known as 2'-O-Methyl-CCPA, is a chemical compound that serves as an inhibitor and agonist in various biological processes. It is characterized by its ability to modulate specific receptors and enzymes, making it a valuable tool in research and pharmaceutical development.
Uses
Used in Pharmaceutical Research:
2'-MeCCPA is used as an inhibitor for forskolin-stimulated adenylyl cyclase, which plays a crucial role in the regulation of cellular processes such as signal transduction and second messenger production. This application is essential for understanding the mechanisms of various diseases and developing targeted therapies.
Used in Neuropharmacology:
As a selective A1 adenosine receptor agonist, 2'-MeCCPA is used in the study of central nervous system functions and the development of drugs targeting neurological disorders. Its ability to selectively activate A1 adenosine receptors makes it a valuable tool for investigating the role of these receptors in cognitive processes, sleep regulation, and other neurological functions.
Biological Activity
Potent and highly selective agonist at A 1 adenosine receptors (K i values are 3.3, 9580, 37600 and 1150 nM for human recombinant A 1 , A 2A , A 2B and A 3 receptors respectively). Acts as a full agonist; inhibits forskolin-stimulated adenylyl cyclase activity in rat cortical membranes with an IC 50 value of 13.1 nM.
Check Digit Verification of cas no
The CAS Registry Mumber 205171-12-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,5,1,7 and 1 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 205171-12:
(8*2)+(7*0)+(6*5)+(5*1)+(4*7)+(3*1)+(2*1)+(1*2)=86
86 % 10 = 6
So 205171-12-6 is a valid CAS Registry Number.
InChI:InChI=1/C16H22ClN5O4/c1-16(25)11(24)9(6-23)26-14(16)22-7-18-10-12(19-8-4-2-3-5-8)20-15(17)21-13(10)22/h7-9,11,14,23-25H,2-6H2,1H3,(H,19,20,21)/t9-,11?,14-,16-/m1/s1