2052-46-2

Basic information

• Product Name: N,N-DIMETHYL-P-PHENYLENEDIAMINE MONOHYDROCHLORIDE
• Synonyms: 4-benzenediamine,n,n-dimethyl-monohydrochloride;n,n-dimethyl-1,4-benzenediaminemonohydrochloride;n,n-dimethyl-p-phenylenediaminmonohydrochloride;4-AMINO-N,N-DIMETHYLANILINE MONOHYDROCHLORIDE;N,N-DIMETHYL-1,4-PHENYLENEDIAMINE MONOHYDROCHLORIDE;N,N-DIMETHYL-1,4-PHENYLENEDIAMINE HYDROCHLORIDE;N,N-DIMETHYL-P-PHENYLENEDIAMINE HYDROCHLORIDE;N,N-DIMETHYL-P-PHENYLENEDIAMINE MONOHYDROCHLORIDE
• CAS NO: 2052-46-2
• Molecular Formula: C₈H₁₂N₂*ClH
• Molecular Weight: 172.66
• EINECS: 218-146-0
• Mol File: 2052-46-2.mol
• Article Data: 1

Chemical Properties

• Melting Point: 215 °C (dec.)(lit.)
• Boiling Point: 211.6°Cat760mmHg
• Flash Point: 84.2°C
• Appearance: /
• Density: 0.94g/cm³
• Storage Temp.: −20°C
• Solubility: DMSO (Slightly), Methanol (Slightly, Sonicated)
• Stability: Hygroscopic
• BRN: 4546912
• CAS DataBase Reference: N,N-DIMETHYL-P-PHENYLENEDIAMINE MONOHYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-DIMETHYL-P-PHENYLENEDIAMINE MONOHYDROCHLORIDE(2052-46-2)
• EPA Substance Registry System: N,N-DIMETHYL-P-PHENYLENEDIAMINE MONOHYDROCHLORIDE(2052-46-2)

Safety Data

• Hazard Codes: T
• Statements: 23/24/25-43
• Safety Statements: 36/37-45
• RIDADR: UN 2811 6.1/PG 2
• WGK Germany: 3
• RTECS: ST1750000
• F: 3-8-10
• HazardClass: 6.1(a)
• PackingGroup: II
• Hazardous Substances Data: 2052-46-2(Hazardous Substances Data)

Usage

Description

N,N-DIMETHYL-P-PHENYLENEDIAMINE MONOHYDROCHLORIDE, also known as 4-Dimethylamineaniline Hydrochloride, is a brown-black to black crystalline powder with specific chemical properties. It is a compound that has been identified for its potential applications in various industries, particularly in the field of medicine and dye production.

Uses

Used in Pharmaceutical Industry:
N,N-DIMETHYL-P-PHENYLENEDIAMINE MONOHYDROCHLORIDE is used as a therapeutic agent for treating tauopathies, a group of neurodegenerative diseases characterized by the accumulation of abnormal tau protein in the brain. Its application in this field is due to its potential to modulate the underlying pathological processes associated with these conditions.
Used in Dye Industry:
N,N-DIMETHYL-P-PHENYLENEDIAMINE MONOHYDROCHLORIDE is used as a chemical intermediate in the production of dyes and metabolites. Its unique chemical structure allows it to be a valuable component in the synthesis of various dye compounds, contributing to the color and stability of the final products.

InChI:InChI=1/C8H12N2.ClH/c1-10(2)8-5-3-7(9)4-6-8;/h3-6H,9H2,1-2H3;1H

Upstream product

• 74886-84-3 methyl red 
• 502-02-3 4-[(E)-2-[4-(dimethylamino)phenyl]diazen-1-yl]benzene-1-sulfonic acid 

Downstream Products

• 111811-34-8 5-(4'-dimethylaminophenylimino)quinolin-8-one 
• 120015-13-6 7-chloro-5-(4'-dimethylaminophenylimino)quinoline-8-one 
• 33624-86-1 Wursters Rot 
• 99-98-9 N,N-dimethyl-p-phenylenediamine radical cation 
• 102780-60-9 2,5-bis<<(4-dimethylamino)phenyl>amino>-1,4-benzoquinone 
• 7512-47-2 chloro-[1,4]-benzoquinone-4-(4-dimethylamino-phenylimine) 
• 64693-19-2 methyl-[1,4]benzoquinone-4-(4-dimethylamino-phenylimine) 
• 64693-21-6 acetylamino-[1,4]benzoquinone-4-(4-dimethylamino-phenylimine) 
• 2150-58-5 phenol blue 
• 160534-31-6 <2-(N,N-dimethyl-p-phenylenediamino)-vinyl> phenyl ketone 
• 2131-64-8 4-isothiocyanato-N,N-dimethylaniline 
• 612840-10-5 benzene-1,3,5-tricarboxylic acid tris-[(4-dimethylamino-phenyl)-amide] 
• 22283-43-8 1-(4-Dimethylaminophenyl)-thioharnstoff 

Relevant articles and documents

A simple reduction method of azo-compounds to amines using Fe powder in the presence of NH4Cl

A series of azo-compounds were reduced to related aromatic amines in the presence of Fe powder and ammonium chloride. This one step protocol led to the formation of products in middle to high yields, especially when electron releasing substituted aromatic azo-compounds were reduced.