205442-90-6

Basic information

• Product Name: (3S,5S,7aR)-3,5-diphenylhexahydropyrrolo<2,1-b><1,3>oxazole
• Synonyms: (3S,5S,7aR)-3,5-diphenylhexahydropyrrolo<2,1-b><1,3>oxazole
• CAS NO: 205442-90-6
• Molecular Weight: 265.355
• Mol File: 205442-90-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (3S,5S,7aR)-3,5-diphenylhexahydropyrrolo<2,1-b><1,3>oxazole(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,5S,7aR)-3,5-diphenylhexahydropyrrolo<2,1-b><1,3>oxazole(205442-90-6)
• EPA Substance Registry System: (3S,5S,7aR)-3,5-diphenylhexahydropyrrolo<2,1-b><1,3>oxazole(205442-90-6)

Safety Data

• Hazardous Substances Data: 205442-90-6(Hazardous Substances Data)

Upstream product

• 1071226-95-3 (2S)-2-((1S)-4-methoxy-1-phenylbut-3-enylamino)-2-phenylethanol 
• 100-58-3 phenylmagnesium bromide 
• 205442-89-3 (3S,5R,7aR)-5-(benzotriazol-1-yl)-3-phenyl<2,1-b>oxazolopyrrolidine 
• 28557-00-8 phenylzinc chloride 

Relevant articles and documents

Palladium-catalyzed cyclization of unsaturated β-amino alcohols: A new access to enantiopure bicyclic oxazolidines

Image Presented Chiral unsaturated β-amino alcohols possessing a dialkylamino function cyclize in the presence of Pd(II) catalysts and reoxidants to afford enantiopure bicyclic oxazolidines with total regio- and stereocontrol. The scope and limitations of

Asymmetric syntheses of 2-substituted and 2,5-disubstituted pyrrolidines from (3S,5R,7aR)-5-(benzotriazol-1-yl)-3-phenyl[2,1-b]oxazolopyrrolidine

Benzotriazole, 2,5-dimethoxytetrahydrofuran, and (S)-phenylglycinol in one step gave 80% of (3S, 5R,7aR)-5-(benzotriazol-1-yl)-3-phenyl-[2,1- b]oxazolopyrrolidine (6), whose crystal structure was confirmed by X-ray crystallography. Novel chiral pyrrolidine synthon 6 reacts with organosilicon (allyltrimethylsilanes and vinyloxytrimethylsilanes), organophosphorus, organozinc, and Grignard reagents to afford chiral 2-substituted and 2,5- disubstituted pyrrolidines.