205443-00-1

Basic information

• Product Name: (S)-2-((2R,5R)-2,5-Diphenethyl-pyrrolidin-1-yl)-2-phenyl-ethanol
• Synonyms: (S)-2-((2R,5R)-2,5-Diphenethyl-pyrrolidin-1-yl)-2-phenyl-ethanol
• CAS NO: 205443-00-1
• Molecular Weight: 399.576
• Mol File: 205443-00-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-2-((2R,5R)-2,5-Diphenethyl-pyrrolidin-1-yl)-2-phenyl-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-((2R,5R)-2,5-Diphenethyl-pyrrolidin-1-yl)-2-phenyl-ethanol(205443-00-1)
• EPA Substance Registry System: (S)-2-((2R,5R)-2,5-Diphenethyl-pyrrolidin-1-yl)-2-phenyl-ethanol(205443-00-1)

Safety Data

• Hazardous Substances Data: 205443-00-1(Hazardous Substances Data)

Upstream product

• 205442-89-3 (3S,5R,7aR)-5-(benzotriazol-1-yl)-3-phenyl<2,1-b>oxazolopyrrolidine 
• 3277-89-2 phenethylmagnesium bromide 

Relevant articles and documents

Pyrrolidine analogues of lobelane: Relationship of affinity for the dihydrotetrabenazine binding site with function of the vesicular monoamine transporter 2 (VMAT2)

Ring size reduction of the central piperidine ring of lobelane yielded pyrrolidine analogues that showed marked inconsistencies in their ability to bind to the dihydrotetrabenazine (DTBZ) binding site on the vesicular monoamine transporter-2 (VMAT2) and t

A short asymmetric synthesis of 2,5-disubstituted pyrrolidines

A novel approach to chiral 2,5-disubstituted pyrrolidines, starting from chiral 2-phenyl-glycimol, 1,5-dimethoxytetrahydrofuran, and benzotriazole, involves the diastereoselective substitution by Grignard reagents of a benzotriazolyl group in a crystalline intermediate obtained in high yield.